Protein: PPARD
Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)

Gene: PPARD
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q03181

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 - transcription coactivator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

975432

NCOA1
Nuclear receptor coactivator 1

5

20

Small-scale

0.916

High

587153

RXRA
Retinoic acid receptor RXR-alpha

5

20

Small-scale

0.912

High

975430

NCOA2
Nuclear receptor coactivator 2

2

20

Small-scale

0.778

High

975487

NCOA3
Nuclear receptor coactivator 3

2

20

Small-scale

0.778

High

659703

RXRB
Retinoic acid receptor RXR-beta

2

20

Small-scale

0.757

High

818868

RXRG
Retinoic acid receptor RXR-gamma

2

20

Small-scale

0.757

High

874376

NR1H2
Oxysterols receptor LXR-beta

1

20

Small-scale

0.692

High

975424

NR1H3
Oxysterols receptor LXR-alpha

1

20

Small-scale

0.692

High

261474

NCOR1
Nuclear receptor corepressor 1

4

20

Small-scale

0.685

High

169279

MDM4
Protein Mdm4

3

8

High-throughput

0.667

High

475000

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

8

High-throughput

0.667

High

962739

MDM2
E3 ubiquitin-protein ligase Mdm2

3

8

High-throughput

0.667

High

975464

RNF31
E3 ubiquitin-protein ligase RNF31

3

8

High-throughput

0.667

High

975479

TRM6
tRNA

3

0

High-throughput

0.638

High

975486

NCOR2
Nuclear receptor corepressor 2

2

20

Small-scale

0.625

High

975426

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.624

High

975429

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

20

High-throughput

0.621

High

975417

PPARD
Peroxisome proliferator-activated receptor delta

1

20

Small-scale

0.618

High

975463

ZN837
Zinc finger protein 837

2

1

High-throughput

0.606

High

975478

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

2

20

Small-scale

0.602

High

177266

HDAC3
Histone deacetylase 3

2

20

Small-scale

0.595

High

975420

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.594

High

776654

STAT3
Signal transducer and activator of transcription 3

2

16

High-throughput

0.594

High

431759

HS90A
Heat shock protein HSP 90-alpha

2

17

Small-scale

0.586

High

975477

NSE4A
Non-structural maintenance of chromosomes element 4 homolog A

2

0

High-throughput

0.585

High

975418

TF65
Transcription factor p65

2

20

Small-scale

0.584

High

232114

KDM1A
Lysine-specific histone demethylase 1A

1

18

High-throughput

0.573

High

975436

OTUD3
OTU domain-containing protein 3

1

4

Small-scale

0.561

High

136009

ACACB
Acetyl-CoA carboxylase 2

1

1

High-throughput

0.536

High

150954

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

8

High-throughput

0.536

High

152871

APAF
Apoptotic protease-activating factor 1

1

20

High-throughput

0.536

High

231296

GANP
Germinal-center associated nuclear protein

1

17

High-throughput

0.536

High

279012

RAD17
Cell cycle checkpoint protein RAD17

1

4

High-throughput

0.536

High

658349

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.536

High

781167

ETV3
ETS translocation variant 3

1

5

High-throughput

0.536

High

840369

ERF
ETS domain-containing transcription factor ERF

1

5

High-throughput

0.536

High

964168

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

975419

DPOE1
DNA polymerase epsilon catalytic subunit A

1

2

High-throughput

0.536

High

975421

TBL3
Transducin beta-like protein 3

1

16

High-throughput

0.536

High

975423

TRI32
E3 ubiquitin-protein ligase TRIM32

1

18

High-throughput

0.536

High

975425

TBB3
Tubulin beta-3 chain

1

10

High-throughput

0.536

High

975441

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.536

High

975442

SAMD1
Sterile alpha motif domain-containing protein 1

1

16

High-throughput

0.536

High

975445

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

9

High-throughput

0.536

High

975446

TBA1A
Tubulin alpha-1A chain

1

16

High-throughput

0.536

High

975448

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

3

High-throughput

0.536

High

975450

MEX3D
RNA-binding protein MEX3D

1

7

High-throughput

0.536

High

975454

CTF18
Chromosome transmission fidelity protein 18 homolog

1

14

High-throughput

0.536

High

975460

N42L2
NEDD4-binding protein 2-like 2

1

1

High-throughput

0.536

High

975462

NACC2
Nucleus accumbens-associated protein 2

1

20

High-throughput

0.536

High

975465

TONSL
Tonsoku-like protein

1

16

High-throughput

0.536

High

975467

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

16

High-throughput

0.536

High

975474

TF7L2
Transcription factor 7-like 2

1

17

High-throughput

0.536

High

975481

TTF2
Transcription termination factor 2

1

20

High-throughput

0.536

High

975485

TF3C3
General transcription factor 3C polypeptide 3

1

13

High-throughput

0.536

High

889230

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.523

High

359869

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

17

High-throughput

0.515

High

791498

HD
Huntingtin

1

4

High-throughput

0.515

High

975447

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

8

High-throughput

0.515

High

176586

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

975431

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.513

High

975435

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.513

High

975440

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.513

High

975453

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

975459

SYMPK
Symplekin

1

0

High-throughput

0.513

High

975466

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

975482

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

975484

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.513

High

171391

SMAD9
Mothers against decapentaplegic homolog 9

1

13

High-throughput

0.508

High

238550

ANM3
Protein arginine N-methyltransferase 3

1

19

High-throughput

0.508

High

309843

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

8

Small-scale

0.501

High

880690

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.501

High

975437

CE350
Centrosome-associated protein 350

1

7

Small-scale

0.501

High

975458

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

975427

RIN1
Ras and Rab interactor 1

1

1

High-throughput

0.489

High

975428

CUL7
Cullin-7

1

1

High-throughput

0.489

High

975433

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

2

High-throughput

0.489

High

975438

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

1

High-throughput

0.489

High

975443

DNMBP
Dynamin-binding protein

1

9

High-throughput

0.489

High

975444

STXB4
Syntaxin-binding protein 4

1

7

High-throughput

0.489

High

975449

HOOK3
Protein Hook homolog 3

1

14

High-throughput

0.489

High

975451

RHPN2
Rhophilin-2

1

12

High-throughput

0.489

High

975455

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

11

High-throughput

0.489

High

975461

ARHG1
Rho guanine nucleotide exchange factor 1

1

13

High-throughput

0.489

High

975468

IF140
Intraflagellar transport protein 140 homolog

1

8

High-throughput

0.489

High

975472

K1671
Uncharacterized protein KIAA1671

1

1

High-throughput

0.489

High

975473

IF122
Intraflagellar transport protein 122 homolog

1

16

High-throughput

0.489

High

975475

ABCF3
ATP-binding cassette sub-family F member 3

1

2

High-throughput

0.489

High

449862

STP1
Spermatid nuclear transition protein 1

1

2

Small-scale

0.481

High

670692

PRDX6
Peroxiredoxin-6

1

7

High-throughput

0.481

High

713495

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.481

High

906997

PRS8
26S proteasome regulatory subunit 8

1

18

High-throughput

0.481

High

975457

PROX1
Prospero homeobox protein 1

1

3

High-throughput

0.481

High

975469

RANB9
Ran-binding protein 9

1

17

High-throughput

0.481

High

130856

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

6

High-throughput

0.479

High

438091

HS90B
Heat shock protein HSP 90-beta

1

17

High-throughput

0.479

High

575386

EGR1
Early growth response protein 1

1

4

Small-scale

0.479

High

587539

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.479

High

771926

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.479

High

786318

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.479

High

975456

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.479

High

975470

MINT
Msx2-interacting protein

1

14

Small-scale

0.479

High

975480

APC7
Anaphase-promoting complex subunit 7

1

8

High-throughput

0.479

High

543015

GLNA
Glutamine synthetase

1

0

High-throughput

0.460

High

314753

PSMG1
Proteasome assembly chaperone 1

1

0

Small-scale

0.458

High

574525

ITB5
Integrin beta-5

1

1

High-throughput

0.439

High

888850

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

975434

Q4KMX6
ANAPC7 protein

1

7

High-throughput

0.407

High

300893

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.279

Low

975422

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

975439

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

0

High-throughput

0.279

Low

975452

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.279

Low

975471

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.279

Low

975483

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.279

Low

975476

RIC8B
Synembryn-B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024