Protein: STEA3
Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde)

Gene: STEA3, STEAP3
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q658P3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005771 - multivesicular body
GO:0005886 - plasma membrane
GO:0006826 - iron ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1225923

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.811

High

1029606

CD83
CD83 antigen

2

0

High-throughput

0.770

High

1225880

STEA3
Metalloreductase STEAP3

1

1

Small-scale

0.692

High

373991

RASN
GTPase NRas

4

5

High-throughput

0.672

High

1225883

S39A4
Zinc transporter ZIP4

3

1

High-throughput

0.667

High

774411

BASI
Basigin

4

0

High-throughput

0.664

High

375610

RASK
GTPase KRas

3

5

High-throughput

0.640

High

639381

5NTD
5'-nucleotidase

3

0

High-throughput

0.638

High

1225886

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

3

0

High-throughput

0.638

High

1225893

TEFF1
Tomoregulin-1

3

0

High-throughput

0.638

High

596753

DPEP1
Dipeptidase 1

2

1

High-throughput

0.628

High

251222

RNBP6
Ran-binding protein 6

2

0

High-throughput

0.602

High

1032594

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

1086010

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.602

High

1225881

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.602

High

1225904

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.602

High

845678

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

1004089

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.586

High

1010050

DLK1
Protein delta homolog 1

2

0

High-throughput

0.585

High

1225882

LTOR1
Ragulator complex protein LAMTOR1

2

0

High-throughput

0.585

High

374677

RASH
GTPase HRas

2

3

High-throughput

0.584

High

540497

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

976333

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.584

High

978080

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

1225907

SNX27
Sorting nexin-27

2

1

Small-scale

0.584

High

1225909

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

2

Small-scale

0.552

High

127689

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

1

High-throughput

0.536

High

164925

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

1

High-throughput

0.536

High

850782

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

1

High-throughput

0.536

High

888892

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.536

High

1146555

TMED2
Transmembrane emp24 domain-containing protein 2

1

1

High-throughput

0.536

High

1225884

PARM1
Prostate androgen-regulated mucin-like protein 1

1

1

High-throughput

0.536

High

630840

RAB4A
Ras-related protein Rab-4A

2

2

High-throughput

0.533

High

303684

JTB
Protein JTB

1

0

High-throughput

0.513

High

406974

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.513

High

845514

PI2R
Prostacyclin receptor

1

0

High-throughput

0.513

High

851138

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

0

High-throughput

0.513

High

1154644

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1225890

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

1225911

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1225918

LRC4C
Leucine-rich repeat-containing protein 4C

1

0

High-throughput

0.513

High

1225921

RPRM
Protein reprimo

1

0

High-throughput

0.513

High

137740

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.489

High

952500

CTXN1
Cortexin-1

1

1

High-throughput

0.489

High

126647

RHOD
Rho-related GTP-binding protein RhoD

1

11

High-throughput

0.479

High

189629

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

226072

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

341082

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

412082

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

466309

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

560423

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

562125

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

581109

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

601328

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

604033

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

605715

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.479

High

630542

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.479

High

631285

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

641194

FGFR2
Fibroblast growth factor receptor 2

1

4

High-throughput

0.479

High

648554

FGFR4
Fibroblast growth factor receptor 4

1

5

High-throughput

0.479

High

710300

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.479

High

900862

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

901304

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

901871

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

910094

RND2
Rho-related GTP-binding protein RhoN

1

12

High-throughput

0.479

High

941792

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

945020

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.479

High

953505

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

955285

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

962155

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

962767

RND3
Rho-related GTP-binding protein RhoE

1

12

High-throughput

0.479

High

988439

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

1015518

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

1031414

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1087148

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1144956

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1146424

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

1147348

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.479

High

1151736

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

1159503

NTRK2
BDNF/NT-3 growth factors receptor

1

4

High-throughput

0.479

High

1225888

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.479

High

1225891

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.479

High

1225895

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1225896

ARL14
ADP-ribosylation factor-like protein 14

1

1

High-throughput

0.479

High

1225901

RND1
Rho-related GTP-binding protein Rho6

1

12

High-throughput

0.479

High

1225906

RHOV
Rho-related GTP-binding protein RhoV

1

9

High-throughput

0.479

High

1225913

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1225914

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.479

High

1225916

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.479

High

1225920

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

1225927

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1225928

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.479

High

1225930

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

1225902

BAD
Bcl2-associated agonist of cell death

1

0

High-throughput

0.460

High

133756

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

218314

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

241974

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

390614

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

463584

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

556148

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

692998

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

715629

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

764368

CTNA1
Catenin alpha-1

1

0

Small-scale

0.458

High

880577

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

975087

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

986487

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

989003

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

1004698

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1041118

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1159690

OCLN
Occludin

1

0

High-throughput

0.458

High

1163355

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1225887

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1225889

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1225898

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1225915

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1225926

ANFY1
Rabankyrin-5

1

0

High-throughput

0.458

High

1093522

TRDN
Triadin

1

1

High-throughput

0.445

High

179931

BET1
BET1 homolog

1

1

High-throughput

0.437

High

956339

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.437

High

1225919

SAR1A
Small COPII coat GTPase SAR1A

1

3

High-throughput

0.437

High

388418

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

722487

CTR1
High affinity cationic amino acid transporter 1

1

0

High-throughput

0.426

High

880840

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

1225917

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

1225894

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

1225897

TEX29
Testis-expressed protein 29

3

0

High-throughput

0.347

High

1198294

TIGD5
Tigger transposable element-derived protein 5

2

0

High-throughput

0.328

High

239374

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.288

High

280925

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

387530

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.279

Low

1225885

LCTL
Lactase-like protein

1

0

High-throughput

0.279

Low

1225905

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

1225908

SG3A1
Secretoglobin family 3A member 1

1

0

High-throughput

0.279

Low

1225910

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.279

Low

1225922

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.279

Low

1225925

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1225929

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.279

Low

1225899

TT21A
Tetratricopeptide repeat protein 21A

1

0

High-throughput

0.269

Low

1225900

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.251

Low

139896

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

176492

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

327311

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

417496

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

1225892

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1225903

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1225924

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1225912

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025