HitPredict

Interactor 1: PSA1 (P21243)
Proteasome subunit alpha type-1 (Macropain subunit C7-alpha) (Multicatalytic endopeptidase complex C7) (Proteasome component C7-alpha) (Proteasome component Y8) (Proteinase YSCE subunit 7) (SCL1 suppressor protein)
Gene: SCL1

Interactor 2: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 11805826, 16429126, 32868373, 22940862, 14759368, 16554755, 18467557, 37968396, 15253422
Identification Methods tandem affinity purification, affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 252
Sc

1 250
+ Zm
+ Dm
+ Sp
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp

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Last updated: 15 Jul 2024