HitPredict

Interactor 1: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	23332755, 37968396, 19536198
Identification Methods	biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006364 - rRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 576 Sc			1 613
+	Sc
		510246 PWP1_YEAST (1-576): 9.91e-105: 328: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		630868 NLE1_YEAST (206-564): 3.22e-61: 212: 13.61		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		744626 TAF5_YEAST (376-558): 3.79e-25: 112: 10.50		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511028 TAF5_YEAST (376-558): 3.79e-25: 112: 10.50		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		765946 HAT2_YEAST (273-513): 1.44e-16: 83.8: 17.53		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		768703 PFS2_YEAST (275-451): 8.04e-16: 82.3: 23.16		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511426 HAT2_YEAST (273-513): 1.44e-16: 83.8: 17.53		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		511705 PFS2_YEAST (275-451): 8.04e-16: 82.3: 23.16		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		564125 POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19		HSP76_HUMAN (3-612): 0: 898: 58.82
+	Hs
		504412 POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		714020 POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19		HS71L_HUMAN (5-612): 0: 893: 59.51
+	Hs
		503817 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		564207 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		HSP76_HUMAN (3-612): 0: 898: 58.82
+	Hs
		504948 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Mm
		926171 FZR1_MOUSE (337-559): 1.97e-22: 102: 16.96		HSP7C_MOUSE (5-612): 0: 896: 60.00
+	Hs
		714094 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		HS71L_HUMAN (5-612): 0: 893: 59.51
+	Hs
		871827 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		HSP72_HUMAN (4-612): 0: 888: 60.13
+	Ce
		450531 LIN53_CAEEL (330-523): 1.2e-19: 93.4: 16.10		HSP1_CAEEL (5-612): 0: 884: 59.74
+	Hs
		504455 UTP15_HUMAN (283-503): 3.98e-15: 80.4: 22.62		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		450018 TAF5_YEAST (376-558): 3.79e-25: 112: 10.50		HSP73_YEAST (9-611): 0: 677: 60.66