HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: CRACD (Q6ZU35)
Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics)
Gene: CRACD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2647 Hs			1 1233
+	Hs
		99712 FLNA_HUMAN (1-2647): 0: 2776: 100.00		F5H1N7_HUMAN (41-1233): 6.42e-173: 546: 100.00
+	Hs
		597985 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		598129 FLNA_HUMAN (1-2647): 0: 2776: 100.00		PLEC_HUMAN (69-693): 1.83e-11: 71.2: 10.88
+	Hs
		598338 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYO5C_HUMAN (265-545): 5.44e-10: 66.1: 14.39
+	Hs
		148392 FLNA_HUMAN (1-2647): 0: 2776: 100.00		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		261212 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		148205 FLNB_HUMAN (28-2647): 0: 2710: 69.63		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		148807 FLNC_HUMAN (32-2647): 0: 1432: 35.96		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		963324 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		963335 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		ITSN1_HUMAN (163-511): 8.51e-29: 127: 17.71
+	Hs
		724781 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		521484 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		963431 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MYO5C_HUMAN (265-545): 5.44e-10: 66.1: 14.39
+	Hs
		148690 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		148330 SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		148463 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		521459 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		148339 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		148722 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		148171 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27