HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: WDTC1 (Q8N5D0)
WD and tetratricopeptide repeats protein 1
Gene: WDTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 677
+	Hs
		598155 FLNA_HUMAN (1-2647): 0: 2776: 100.00		DCAF6_HUMAN (479-669): 8.52e-41: 161: 29.85
+	Hs
		598163 FLNA_HUMAN (1-2647): 0: 2776: 100.00		DCAF8_HUMAN (511-677): 1.89e-31: 131: 29.15
+	Hs
		597996 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LIS1_HUMAN (486-675): 1.15e-24: 109: 11.00
+	Hs
		598240 FLNA_HUMAN (1-2647): 0: 2776: 100.00		POC1B_HUMAN (488-664): 5.31e-23: 104: 12.36
+	Hs
		598040 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5_HUMAN (519-664): 4.67e-21: 96.8: 12.25
+	Hs
		598209 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5B_HUMAN (536-664): 1.93e-19: 91.8: 15.39
+	Hs
		598345 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NLE1_HUMAN (571-658): 2.46e-14: 77.9: 20.23
+	Hs
		598268 FLNA_HUMAN (1-2647): 0: 2776: 100.00		SNR40_HUMAN (5-71): 6.38e-13: 72.5: 22.39
+	Hs
		261236 FLNB_HUMAN (28-2647): 0: 2710: 69.63		WDR5_HUMAN (519-664): 4.67e-21: 96.8: 12.25
+	Mm
		1112495 Q3UGX2_MOUSE (2-460): 6.8e-117: 418: 23.77		WDTC1_MOUSE (1-677): 9.05e-131: 403: 93.66
+	Hs
		903137 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		WDR5_HUMAN (519-664): 4.67e-21: 96.8: 12.25
+	Hs
		957556 PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81		SNR40_HUMAN (5-71): 6.38e-13: 72.5: 22.39