HitPredict

Interactor 1: AOFA (P21397)
Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)
Gene: MAOA

Interactor 2: AOFB (P27338)
Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)
Gene: MAOB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 28514442, 30021884, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Amino_oxidase~Amino_oxidase
Common GO terms GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0008131 - primary amine oxidase activity
GO:0042420 - dopamine catabolic process
GO:0050660 - flavin adenine dinucleotide binding
and 2 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 527
Hs

1 520
+ At
+ Hs
+ Hs
+ Sp
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024