Interactor 1: RIR1 (P21524)
Ribonucleoside-diphosphate reductase large chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R1 subunit 1) (Ribonucleotide reductase large subunit 1)
Gene: RNR1

Interactor 2: RIR3 (P21672)
Ribonucleoside-diphosphate reductase large chain 2 (EC 1.17.4.1) (Ribonucleotide reductase DNA damage-inducible regulatory subunit 2) (Ribonucleotide reductase R1 subunit 2) (Ribonucleotide reductase large subunit 2)
Gene: RNR3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 11074005, 11805837, 16554755, 37968396
Identification Methods two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-cone~ATP-cone, ATP-cone~Ribonuc_red_lgC, ATP-cone~Ribonuc_red_lgN, Ribonuc_red_lgC~Ribonuc_red_lgC, Ribonuc_red_lgC~Ribonuc_red_lgN
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0006260 - DNA replication
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 888
Sc

1 869
+ Sc
+ Hs
+ Vv
+ Ec
+ Ha
+ Hh
+ Hh
+ Ha
+ Mb

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Last updated: 15 Jul 2024