HitPredict

Interactor 1: CNR1 (P21554)
Cannabinoid receptor 1 (CB-R) (CB1) (CANN6)
Gene: CNR1

Interactor 2: AA2AR (P29274)
Adenosine receptor A2a
Gene: ADORA2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 17356572, 28102227
Identification Methods fluorescent resonance energy transfer, bimolecular fluorescence complementation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005886 - plasma membrane
GO:0007188 - adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0042734 - presynaptic membrane
GO:0098978 - glutamatergic synapse
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 472
Hs

1 412
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024