HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: PDLI2 (Q96JY6)
PDZ and LIM domain protein 2 (PDZ-LIM protein mystique)
Gene: PDLIM2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25640309
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 821 Hs			1 352
+	Hs
		507981 FGFR1_HUMAN (1-820): 0: 772: 71.17		SNTB2_HUMAN (5-272): 8.39e-27: 113: 14.08
+	Hs
		507990 FGFR1_HUMAN (1-820): 0: 772: 71.17		SNTB1_HUMAN (4-343): 8.3e-27: 113: 14.93
+	Hs
		608087 FGFR4_HUMAN (22-810): 0: 684: 55.86		PDLI2_HUMAN (1-352): 1.42e-58: 194: 100.00
+	Hs
		609274 FGFR3_HUMAN (10-821): 0: 731: 65.69		SNTB2_HUMAN (5-272): 8.39e-27: 113: 14.08
+	Hs
		609282 FGFR3_HUMAN (10-821): 0: 731: 65.69		SNTB1_HUMAN (4-343): 8.3e-27: 113: 14.93
+	Hs
		607960 FGFR4_HUMAN (22-810): 0: 684: 55.86		SNTB2_HUMAN (5-272): 8.39e-27: 113: 14.08
+	Hs
		607963 FGFR4_HUMAN (22-810): 0: 684: 55.86		SNTB1_HUMAN (4-343): 8.3e-27: 113: 14.93
+	Hs
		608206 FGFR4_HUMAN (22-810): 0: 684: 55.86		GRIP1_HUMAN (27-227): 2.34e-09: 61: 14.36
+	Hs
		968367 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		SNTB2_HUMAN (5-272): 8.39e-27: 113: 14.08
+	Hs
		968375 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		SNTB1_HUMAN (4-343): 8.3e-27: 113: 14.93
+	Hs
		385712 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		SYNP2_HUMAN (5-256): 2.69e-37: 144: 20.30
+	Hs
		872669 EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60		MAGI2_HUMAN (12-160): 8.39e-09: 59.1: 16.99
+	Hs
		434295 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		PDLI7_HUMAN (57-339): 1.13e-11: 67.6: 8.45
+	Hs
		385342 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PDLI5_HUMAN (111-339): 2.24e-10: 63.7: 14.10
+	Hs
		729276 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		SNTB1_HUMAN (4-343): 8.3e-27: 113: 14.93