HitPredict

Interactor 1: RU17 (P17133)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: snRNP-U1-70K

Interactor 2: NCBP1 (Q7K4N3)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: Cbp80

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 448 Dm			1 800
+	Hs
		472681 RU17_HUMAN (1-223): 3.27e-49: 175: 66.96		NCBP1_HUMAN (1-800): 0: 1074: 57.50
+	Hs
		1066628 PABP4_HUMAN (7-200): 8.29e-36: 141: 13.40		NCBP1_HUMAN (1-800): 0: 1074: 57.50
+	Hs
		550245 PABP1_HUMAN (7-185): 8.55e-35: 138: 13.41		NCBP1_HUMAN (1-800): 0: 1074: 57.50
+	Hs
		1066617 ELAV2_HUMAN (93-179): 2.1e-13: 73.3: 24.14		NCBP1_HUMAN (1-800): 0: 1074: 57.50
+	Sc
		757516 RU17_YEAST (3-264): 1.72e-41: 151: 27.78		NCBP1_YEAST (3-629): 0: 566: 20.03
+	Sc
		403436 PABP_YEAST (3-263): 3.31e-33: 133: 13.03		NCBP1_YEAST (3-629): 0: 566: 20.03