Protein: NCBP1
Nuclear cap-binding protein complex subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) (Glycolysis regulation protein 3) (Protein SUT1) (Suppressor of TOP1 protein)

Gene: NCBP1, STO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 147
UniProt ID: P34160

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000243 - commitment complex
GO:0000339 - RNA cap binding
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757550

NCBP2
Nuclear cap-binding protein subunit 2

20

8

Small-scale

0.988

High

757517

NOP3
Serine/arginine

7

11

Small-scale

0.951

High

757515

NAM8
Protein NAM8

5

4

Small-scale

0.919

High

743516

RU1A
U1 small nuclear ribonucleoprotein A

6

0

Small-scale

0.894

High

757492

IF4F2
Eukaryotic initiation factor 4F subunit p130

4

6

High-throughput

0.892

High

757516

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

4

7

High-throughput

0.892

High

757475

YRA2
RNA annealing protein YRA2

6

0

Small-scale

0.887

High

403436

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

4

4

Small-scale

0.886

High

757491

IF4F1
Eukaryotic initiation factor 4F subunit p150

3

4

High-throughput

0.855

High

757511

NRD1
Protein NRD1

4

0

Small-scale

0.853

High

744099

BRR2
Pre-mRNA-splicing helicase BRR2

3

7

High-throughput

0.847

High

757485

NAB3
Nuclear polyadenylated RNA-binding protein 3

3

0

High-throughput

0.811

High

444480

DED1
ATP-dependent RNA helicase DED1

2

3

Small-scale

0.806

High

757553

CWC2
Pre-mRNA-splicing factor CWC2

2

1

High-throughput

0.789

High

740855

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

2

6

High-throughput

0.759

High

638005

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

2

4

High-throughput

0.754

High

757472

NCBP1
Nuclear cap-binding protein complex subunit 1

2

1

High-throughput

0.754

High

757546

SUB2
ATP-dependent RNA helicase SUB2

2

6

Small-scale

0.754

High

757555

YRA1
RNA annealing protein YRA1

2

6

Small-scale

0.754

High

757523

IMA1
Importin subunit alpha

7

5

High-throughput

0.742

High

517971

SSBP1
Single-stranded nucleic acid-binding protein

1

7

High-throughput

0.691

High

750223

PRP40
Pre-mRNA-processing protein PRP40

4

1

High-throughput

0.691

High

757500

SMD3
Small nuclear ribonucleoprotein Sm D3

4

2

High-throughput

0.691

High

757530

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

5

High-throughput

0.691

High

757541

SMD2
Small nuclear ribonucleoprotein Sm D2

4

2

High-throughput

0.691

High

757547

LUC7
Protein LUC7

4

2

High-throughput

0.691

High

757494

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

1

High-throughput

0.686

High

757536

RU1C
U1 small nuclear ribonucleoprotein C

5

0

High-throughput

0.684

High

757510

THO2
THO complex subunit 2

4

1

Small-scale

0.678

High

757513

RUXF
Small nuclear ribonucleoprotein F

4

1

High-throughput

0.678

High

757540

IMB1
Importin subunit beta-1

4

1

High-throughput

0.678

High

453925

IF4E
Eukaryotic translation initiation factor 4E

3

1

High-throughput

0.667

High

757535

RSE1
Pre-mRNA-splicing factor RSE1

3

4

High-throughput

0.662

High

656955

BUR1
Serine/threonine-protein kinase BUR1

4

0

Small-scale

0.661

High

757506

SNU71
U1 small nuclear ribonucleoprotein component SNU71

4

0

High-throughput

0.661

High

757520

SMD1
Small nuclear ribonucleoprotein Sm D1

4

0

High-throughput

0.661

High

757531

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

4

0

Small-scale

0.660

High

751722

PRP8
Pre-mRNA-splicing factor 8

3

1

High-throughput

0.656

High

605886

HPR1
THO complex subunit HPR1

4

0

Small-scale

0.648

High

734409

BTAF1
TATA-binding protein-associated factor MOT1

1

2

Small-scale

0.647

High

757495

RUXG
Small nuclear ribonucleoprotein G

3

1

High-throughput

0.643

High

757565

MEX67
mRNA export factor MEX67

3

3

Small-scale

0.640

High

757537

BUR2
Protein BUR2

3

0

Small-scale

0.634

High

438661

SC160
Protein SCP160

2

5

High-throughput

0.621

High

676904

SRO9
RNA-binding protein SRO9

2

4

High-throughput

0.621

High

757514

SEN1
Helicase SEN1

2

2

High-throughput

0.621

High

757521

CUS1
Cold sensitive U2 snRNA suppressor 1

2

1

High-throughput

0.621

High

590189

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

4

High-throughput

0.618

High

664589

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

4

High-throughput

0.618

High

676714

GBP2
Serine/arginine

1

6

Small-scale

0.618

High

744274

CHD1
Chromo domain-containing protein 1

1

1

High-throughput

0.618

High

757484

HRB1
Serine/arginine

1

5

Small-scale

0.618

High

757566

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

7

Small-scale

0.618

High

702239

YJU2
Splicing factor YJU2

3

0

High-throughput

0.616

High

594295

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

0

Small-scale

0.613

High

419397

H2A1
Histone H2A.1

2

0

High-throughput

0.595

High

547865

NHP6B
Non-histone chromosomal protein 6B

2

2

High-throughput

0.588

High

757478

HEK2
Heterogeneous nuclear rnp K-like protein 2

2

5

High-throughput

0.588

High

700088

PRP45
Pre-mRNA-processing protein 45

2

1

High-throughput

0.584

High

738807

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

Small-scale

0.584

High

739126

PRP19
Pre-mRNA-processing factor 19

2

1

High-throughput

0.584

High

757490

PRP39
Pre-mRNA-processing factor 39

2

4

High-throughput

0.584

High

757499

PRP17
Pre-mRNA-processing factor 17

2

1

High-throughput

0.584

High

757533

SYF1
Pre-mRNA-splicing factor SYF1

2

3

High-throughput

0.584

High

757551

RU2A
U2 small nuclear ribonucleoprotein A'

2

2

High-throughput

0.584

High

757559

PRP46
Pre-mRNA-splicing factor PRP46

2

2

High-throughput

0.584

High

757561

AIR2
Protein AIR2

2

1

High-throughput

0.567

High

739851

RPD3
Histone deacetylase RPD3

2

0

High-throughput

0.563

High

757498

MSH4
MutS protein homolog 4

2

0

High-throughput

0.563

High

625084

PRP9
Pre-mRNA-splicing factor PRP9

2

0

High-throughput

0.559

High

757473

MTR2
mRNA transport regulator MTR2

2

0

Small-scale

0.559

High

757538

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.559

High

757558

RUXE
Small nuclear ribonucleoprotein E

2

0

Small-scale

0.559

High

628200

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

4

High-throughput

0.553

High

526320

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

757512

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

757503

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.493

High

502956

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.489

High

757563

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.481

High

757477

MUD2
Splicing factor MUD2

1

0

Small-scale

0.480

High

721819

XPO1
Exportin-1

1

2

Small-scale

0.479

High

739235

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.479

High

757476

SN114
Pre-mRNA-splicing factor SNU114

1

1

High-throughput

0.479

High

757496

MLP2
Protein MLP2

1

3

High-throughput

0.479

High

757502

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.479

High

757505

SF3B1
U2 snRNP component HSH155

1

5

High-throughput

0.479

High

757507

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.479

High

757527

CEF1
Pre-mRNA-splicing factor CEF1

1

1

High-throughput

0.479

High

757539

YTH1
mRNA 3'-end-processing protein YTH1

1

2

Small-scale

0.479

High

757543

CFT1
Protein CFT1

1

4

High-throughput

0.479

High

757545

PRP11
Pre-mRNA-splicing factor PRP11

1

1

High-throughput

0.479

High

757556

BBP
Branchpoint-bridging protein

1

1

Small-scale

0.479

High

757557

CLF1
Pre-mRNA-splicing factor CLF1

1

3

High-throughput

0.479

High

757560

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

634219

NUP1
Nucleoporin NUP1

1

1

High-throughput

0.470

High

739584

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.470

High

757519

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

High-throughput

0.470

High

737817

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.460

High

150161

THP2
THO complex subunit THP2

1

0

High-throughput

0.458

High

638055

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

670546

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

672047

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

706687

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734922

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

751367

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

753229

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.458

High

757479

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

757480

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

757481

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

757483

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

757487

PCF11
Protein PCF11

1

0

Small-scale

0.458

High

757497

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

757501

SAD1
Pre-mRNA-splicing factor SAD1

1

0

High-throughput

0.458

High

757504

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.458

High

757508

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

757509

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

757522

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

757525

ESP1
Separin

1

0

High-throughput

0.458

High

757526

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.458

High

757529

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

757532

CTK1
CTD kinase subunit alpha

1

0

Small-scale

0.458

High

757542

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

757549

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

0

High-throughput

0.458

High

757552

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

757554

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

523519

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

544355

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

597102

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.445

High

757482

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.426

High

757488

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

757518

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

394418

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

510358

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.407

High

757474

LHS1
Heat shock protein 70 homolog LHS1

1

4

High-throughput

0.407

High

757493

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

757544

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

757564

BRR1
Pre-mRNA-splicing factor BRR1

2

0

High-throughput

0.313

High

376287

YPT1
GTP-binding protein YPT1

1

0

Small-scale

0.249

Low

757489

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

757524

ELP4
Elongator complex protein 4

1

0

High-throughput

0.249

Low

757528

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

757548

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.249

Low

752084

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

757486

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

757534

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

757562

YP064
Uncharacterized protein YPR064W

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025