Protein: RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1)

Gene: RU17, SNP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 104
UniProt ID: Q00916

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743544

RU1A
U1 small nuclear ribonucleoprotein A

8

1

Small-scale

0.968

High

1025644

NAM8
Protein NAM8

6

15

Small-scale

0.940

High

817146

RSMB
Small nuclear ribonucleoprotein-associated protein B

6

9

Small-scale

0.937

High

1027992

RU1C
U1 small nuclear ribonucleoprotein C

5

1

High-throughput

0.922

High

1028000

NCBP2
Nuclear cap-binding protein subunit 2

5

20

Small-scale

0.922

High

1027989

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

6

0

Small-scale

0.895

High

757516

NCBP1
Nuclear cap-binding protein complex subunit 1

4

7

High-throughput

0.892

High

820827

RUXG
Small nuclear ribonucleoprotein G

4

12

High-throughput

0.881

High

1027979

NOP3
Serine/arginine

4

20

Small-scale

0.878

High

1027994

SMD2
Small nuclear ribonucleoprotein Sm D2

3

4

High-throughput

0.839

High

1027981

SMD1
Small nuclear ribonucleoprotein Sm D1

3

2

Small-scale

0.827

High

933129

RUXF
Small nuclear ribonucleoprotein F

2

6

High-throughput

0.776

High

847818

SMD3
Small nuclear ribonucleoprotein Sm D3

2

14

High-throughput

0.754

High

1027977

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

2

17

Small-scale

0.754

High

1028001

RU2A
U2 small nuclear ribonucleoprotein A'

2

4

Small-scale

0.754

High

750289

PRP40
Pre-mRNA-processing protein PRP40

7

8

Small-scale

0.745

High

813367

PRP39
Pre-mRNA-processing factor 39

6

7

Small-scale

0.730

High

918222

SNU71
U1 small nuclear ribonucleoprotein component SNU71

8

0

Small-scale

0.716

High

1027997

LUC7
Protein LUC7

5

7

High-throughput

0.714

High

1027988

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

9

High-throughput

0.694

High

403622

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

19

High-throughput

0.691

High

722174

XPO1
Exportin-1

1

12

High-throughput

0.691

High

751774

PRP8
Pre-mRNA-splicing factor 8

3

4

Small-scale

0.680

High

1028004

RUXE
Small nuclear ribonucleoprotein E

1

3

High-throughput

0.665

High

735537

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

7

High-throughput

0.656

High

780844

MUD2
Splicing factor MUD2

3

1

Small-scale

0.640

High

744148

BRR2
Pre-mRNA-splicing helicase BRR2

2

17

Small-scale

0.640

High

815209

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

17

High-throughput

0.621

High

1027998

WHI4
Protein WHI4

1

10

Small-scale

0.621

High

792910

ANM1
Protein arginine N-methyltransferase 1

2

18

Small-scale

0.619

High

741064

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

19

High-throughput

0.618

High

1027982

CUS1
Cold sensitive U2 snRNA suppressor 1

1

2

High-throughput

0.618

High

1028003

BBP
Branchpoint-bridging protein

1

20

Small-scale

0.618

High

646073

KIN3
Serine/threonine-protein kinase KIN3

1

17

High-throughput

0.590

High

454755

KAPR
cAMP-dependent protein kinase regulatory subunit

1

4

High-throughput

0.536

High

545923

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.536

High

633500

PP11
Serine/threonine-protein phosphatase PP1-1

1

9

High-throughput

0.536

High

781722

SA190
SIT4-associating protein SAP190

1

1

High-throughput

0.536

High

798287

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.536

High

828503

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.536

High

1027983

IMA1
Importin subunit alpha

1

1

High-throughput

0.536

High

807123

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

483801

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

1

High-throughput

0.508

High

554763

REV1
DNA repair protein REV1

1

3

High-throughput

0.508

High

577570

CYC8
General transcriptional corepressor CYC8

1

9

High-throughput

0.508

High

687073

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

10

High-throughput

0.508

High

704877

KIP1
Kinesin-like protein KIP1

1

1

High-throughput

0.508

High

721653

RENT1
ATP-dependent helicase NAM7

1

14

Small-scale

0.508

High

915242

ACS2
Acetyl-coenzyme A synthetase 2

1

1

High-throughput

0.508

High

796111

IMB2
Importin subunit beta-2

1

7

Small-scale

0.501

High

676266

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.500

High

453193

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

3

High-throughput

0.489

High

453305

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.489

High

785957

LONM
Lon protease homolog, mitochondrial

1

7

High-throughput

0.489

High

825760

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.489

High

1027985

HAS1
ATP-dependent RNA helicase HAS1

1

16

High-throughput

0.489

High

638928

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.486

High

650004

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.486

High

745492

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.486

High

844365

YCH1
CDC25-like phosphatase YCH1

1

0

High-throughput

0.486

High

1027980

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

High-throughput

0.486

High

1027986

MTND
Acireductone dioxygenase

1

0

High-throughput

0.486

High

1027987

USA1
U1 SNP1-associating protein 1

1

0

Small-scale

0.486

High

1027999

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.486

High

1028002

PALA
pH-response regulator protein palA/RIM20

1

0

High-throughput

0.486

High

740207

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.479

High

666525

DBP2
ATP-dependent RNA helicase DBP2

1

10

High-throughput

0.479

High

707917

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

780209

SN114
Pre-mRNA-splicing factor SNU114

1

10

Small-scale

0.479

High

826053

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

1027993

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

1028005

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

477612

MYO1
Myosin-1

1

3

High-throughput

0.464

High

763482

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.464

High

783882

RM04
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.464

High

745032

YSC84
Protein YSC84

1

9

High-throughput

0.457

High

814254

RV167
Reduced viability upon starvation protein 167

1

6

High-throughput

0.457

High

850465

LSB3
LAS seventeen-binding protein 3

1

7

High-throughput

0.457

High

555133

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

592439

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.457

High

527441

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

739185

PRP19
Pre-mRNA-processing factor 19

1

16

Small-scale

0.445

High

742189

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

804380

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

819522

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

554634

RM02
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.437

High

655503

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.437

High

1027984

NOG1
Nucleolar GTP-binding protein 1

1

6

High-throughput

0.437

High

510732

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.407

High

1027995

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

4

High-throughput

0.407

High

796821

EXO84
Exocyst complex component EXO84

1

0

Small-scale

0.305

High

803842

DOG1
2-deoxyglucose-6-phosphate phosphatase 1

1

0

High-throughput

0.279

Low

830086

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

1027996

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.279

Low

149225

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.265

Low

677837

YCZ1
Uncharacterized protein YCR101C

1

0

High-throughput

0.265

Low

813835

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.265

Low

817812

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

850624

OSW7
Outer spore wall protein 7

1

0

High-throughput

0.265

Low

1027978

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.265

Low

1027990

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.265

Low

1027991

CRR1
Probable glycosidase CRR1

1

0

High-throughput

0.265

Low

464516

CHS1
Chitin synthase 1

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025