HitPredict

Interactor 1: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Interactor 2: CD82 (P27701)
CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
Gene: CD82

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	15492270, 26686862
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 228 Hs			1 267
+	Hs
		602239 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN5_HUMAN (8-267): 5.13e-65: 205: 26.69
+	Hs
		602271 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14
+	Hs
		602230 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		CD151_HUMAN (3-261): 2.39e-58: 188: 27.48
+	Hs
		905534 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		TSN14_HUMAN (10-258): 8.59e-63: 199: 23.14
+	Hs
		279368 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN9_HUMAN (1-265): 2.73e-55: 179: 28.68
+	Hs
		446010 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		CD63_HUMAN (4-258): 5.91e-54: 176: 24.71
+	Hs
		326023 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN15_HUMAN (9-258): 7.16e-52: 172: 18.90
+	Hs
		819445 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		CD151_HUMAN (3-261): 2.39e-58: 188: 27.48
+	Hs
		602238 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		CD81_HUMAN (4-259): 4.59e-49: 163: 22.52
+	Hs
		279369 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		TSN9_HUMAN (1-265): 2.73e-55: 179: 28.68
+	Hs
		602216 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		CD9_HUMAN (2-260): 1.54e-47: 159: 25.19
+	Hs
		326051 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		TSN15_HUMAN (9-258): 7.16e-52: 172: 18.90
+	Hs
		156131 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN4_HUMAN (1-260): 1.03e-43: 149: 27.31
+	Hs
		583857 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		CD53_HUMAN (1-258): 8.88e-44: 149: 29.46
+	Hs
		111521 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		K4DIA7_HUMAN (3-238): 7.48e-50: 165: 26.78
+	Hs
		887767 TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64		CD81_HUMAN (4-259): 4.59e-49: 163: 22.52
+	Hs
		156137 CD81_HUMAN (1-225): 2.3e-53: 173: 43.59		TSN4_HUMAN (1-260): 1.03e-43: 149: 27.31
+	Hs
		237716 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN2_HUMAN (6-151): 1.01e-17: 81.3: 31.29
+	Hs
		237688 CD9_HUMAN (1-228): 5.13e-61: 192: 100.00		TSN1_HUMAN (5-161): 3.89e-14: 71.6: 32.50