Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA
Interactor 2: M3K9 (P80192)
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)
Gene: MAP3K9
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32814053 |
| Identification Methods | two hybrid array, two hybrid pooling approach, validated two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0006468 - protein phosphorylation GO:0106310 - protein serine kinase activity |
| Homologous interactions | 3 |
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Last updated: 11Aug2025