HitPredict

Interactor 1: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Interactor 2: RPAB5 (P22139)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (ABC10-beta) (ABC8) (DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide)
Gene: RPB10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.891

The method score is based on:

Property	Details
Experiments	10393904, 17892321, 16554755, 37968396
Identification Methods	two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	RNA_pol_N~RNA_pol_Rpb2_6
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005736 - RNA polymerase I complex GO:0006360 - transcription by RNA polymerase I and 5 others more... GO:0006361 - transcription initiation at RNA polymerase I promoter GO:0006362 - transcription elongation by RNA polymerase I GO:0006363 - termination of RNA polymerase I transcription GO:0042254 - ribosome biogenesis GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	1203
Sc

1	70

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024