HitPredict

Interactor 1: A5D6Q2 (A5D6Q2)
Ncoa3 protein
Gene: Ncoa3

Interactor 2: PER1 (O35973)
Period circadian protein homolog 1 (mPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui)
Gene: PER1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PAS~PAS_3, PAS_11~PAS_3
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1353 Mm			1 1291
+	Mm
		193652 Q05BA5_MOUSE (1-1353): 1.49e-167: 540: 100.00		PER1_MOUSE (1-1291): 4.71e-164: 526: 100.00
+	Hs
		1075403 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NCOA2_HUMAN (106-1094): 5.52e-134: 448: 13.09
+	Hs
		1306198 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NPAS2_HUMAN (115-961): 6.79e-113: 375: 16.94
+	Hs
		1335642 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ARNT2_HUMAN (61-708): 1.38e-98: 333: 15.64
+	Mm
		1142409 HIF1A_MOUSE (2-679): 1.23e-106: 359: 14.37		BMAL1_MOUSE (32-642): 1.51e-119: 387: 16.23
+	Hs
		1264408 EPAS1_HUMAN (2-800): 6.74e-99: 339: 14.47		BMAL2_HUMAN (38-570): 1.63e-125: 403: 17.44
+	Hs
		1085577 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		HIF1A_HUMAN (113-855): 1.98e-114: 379: 11.37
+	Hs
		126132 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		BMAL1_HUMAN (32-642): 8.02e-115: 374: 16.97
+	Hs
		87730 D0VY79_HUMAN (2-704): 1.09e-102: 348: 14.29		BMAL1_HUMAN (32-642): 8.02e-115: 374: 16.97
+	Hs
		126166 EPAS1_HUMAN (2-800): 6.74e-99: 339: 14.47		BMAL1_HUMAN (32-642): 8.02e-115: 374: 16.97
+	Hs
		1085741 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		X5DP31_HUMAN (61-651): 5.9e-109: 359: 17.14
+	Hs
		1085655 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		EPAS1_HUMAN (110-937): 1.93e-103: 351: 14.99
+	Hs
		1306527 EPAS1_HUMAN (2-800): 6.74e-99: 339: 14.47		EPAS1_HUMAN (110-937): 1.93e-103: 351: 14.99
+	Hs
		1085690 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ARNT2_HUMAN (61-708): 1.38e-98: 333: 15.64
+	Mm
		864794 HIF1A_MOUSE (2-679): 1.23e-106: 359: 14.37		ARNT_MOUSE (23-787): 5.25e-93: 319: 16.07
+	Hs
		1306541 EPAS1_HUMAN (2-800): 6.74e-99: 339: 14.47		ARNT2_HUMAN (61-708): 1.38e-98: 333: 15.64
+	Hs
		649123 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ARNT_HUMAN (23-772): 1.05e-94: 324: 15.38
+	Hs
		649150 EPAS1_HUMAN (2-800): 6.74e-99: 339: 14.47		ARNT_HUMAN (23-772): 1.05e-94: 324: 15.38
+	Hs
		649084 SIM1_HUMAN (2-681): 1.47e-99: 338: 14.53		ARNT_HUMAN (23-772): 1.05e-94: 324: 15.38