Interactor 1: PSB4 (P22141)
Proteasome subunit beta type-4 (Macropain subunit C11) (Multicatalytic endopeptidase complex subunit C11) (Proteasome component C11) (Proteinase YSCE subunit 11)
Gene: PRE1

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 12200147, 11029046, 37968396, 9228276, 15242647, 8628401, 8887631, 21878652, 16284124
Identification Methods coimmunoprecipitation, affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 198
Sc

1 405
+ Dm
+ At
+ At
+ Dm
+ Dm
+ At
+ At
+ At
+ Hs
+ At
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024