HitPredict

Interactor 1: AFT1 (P22149)
Iron-regulated transcriptional activator AFT1 (Activator of iron transcription protein 1)
Gene: AFT1

Interactor 2: GLRX4 (P32642)
Monothiol glutaredoxin-4
Gene: GRX4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	37968396, 17074835, 21299470, 16648636, 23045394
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 690 Sc			1 244
+	Sc
		605258 AFT1_YEAST (1-690): 0: 1222: 100.00		GLRX3_YEAST (1-244): 4.2e-70: 216: 66.67
+	Sc
		977740 AFT2_YEAST (95-434): 6.25e-122: 371: 38.01		GLRX3_YEAST (1-244): 4.2e-70: 216: 66.67