Protein: ITF2
Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2)

Gene: ITF2, Tcf4
Organism: Mus musculus
Interactions: 42
UniProt ID: Q60722

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001093 - TFIIB-class transcription factor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832287

ID3
DNA-binding protein inhibitor ID-3

2

20

Small-scale

0.757

High

688461

TWST1
Twist-related protein 1

1

20

High-throughput

0.724

High

1036062

CTNB1
Catenin beta-1

5

3

Small-scale

0.705

High

1221382

Q6GTZ3
Idb1 protein

1

20

High-throughput

0.698

High

586105

TFE2
Transcription factor E2-alpha

1

13

Small-scale

0.647

High

1221377

ITF2
Transcription factor 4

1

13

Small-scale

0.647

High

1221379

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

20

Small-scale

0.647

High

1221380

HTF4
Transcription factor 12

1

13

Small-scale

0.647

High

682144

RBTN2
Rhombotin-2

1

6

Small-scale

0.621

High

1221399

ASCL3
Achaete-scute homolog 3

1

20

Small-scale

0.621

High

644327

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

20

Small-scale

0.618

High

666142

MYF5
Myogenic factor 5

1

20

Small-scale

0.618

High

1221385

Q6XZL8
Histone-lysine N-methyltransferase, H3 lysine-79 specific

2

1

Small-scale

0.594

High

832350

ID2
DNA-binding protein inhibitor ID-2

1

20

High-throughput

0.590

High

236454

AF10
Protein AF-10

1

7

Small-scale

0.500

High

1021777

SMRC1
SWI/SNF complex subunit SMARCC1

1

3

Small-scale

0.500

High

1221381

TIF1B
Transcription intermediary factor 1-beta

1

6

Small-scale

0.500

High

1221383

SMRC2
SWI/SNF complex subunit SMARCC2

1

5

Small-scale

0.500

High

1221389

RBM14
RNA-binding protein 14

1

1

Small-scale

0.500

High

1221392

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

5

Small-scale

0.500

High

1221393

TF7L2
Transcription factor 7-like 2

1

5

Small-scale

0.500

High

1221396

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

5

Small-scale

0.500

High

1221397

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

Small-scale

0.500

High

1221400

CARM1
Histone-arginine methyltransferase CARM1

1

1

Small-scale

0.500

High

60009

ARI1A
AT-rich interactive domain-containing protein 1A

1

0

Small-scale

0.479

High

312036

ZN326
DBIRD complex subunit ZNF326

1

0

Small-scale

0.479

High

1013584

TNIK
Traf2 and NCK-interacting protein kinase

1

0

Small-scale

0.479

High

1221384

RIF1
Telomere-associated protein RIF1

1

0

Small-scale

0.479

High

1221387

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.479

High

1221388

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

Small-scale

0.479

High

236953

MTG16
Protein CBFA2T3

1

9

Small-scale

0.479

High

1000504

LDB1
LIM domain-binding protein 1

1

2

Small-scale

0.479

High

1221378

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

1

Small-scale

0.479

High

432084

JUN
Transcription factor Jun

1

0

Small-scale

0.458

High

1221390

RBM28
RNA-binding protein 28

1

1

Small-scale

0.457

High

1221391

WDR47
WD repeat-containing protein 47

1

2

Small-scale

0.457

High

1221395

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

1

Small-scale

0.457

High

98203

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

Small-scale

0.445

High

1221386

DACT2
Dapper homolog 2

1

2

Small-scale

0.437

High

1221394

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

Small-scale

0.261

Low

1221398

FLII
Protein flightless-1 homolog

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025