Protein: NUP58
Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1)

Gene: NUP58
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q9BVL2

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0006913 - nucleocytoplasmic transport
GO:0008139 - nuclear localization sequence binding
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1188239

NUP54
Nucleoporin p54

10

19

High-throughput

0.979

High

740247

NUP62
Nuclear pore glycoprotein p62

7

19

High-throughput

0.970

High

1314008

N62CL
Nucleoporin-62 C-terminal-like protein

2

10

High-throughput

0.811

High

1023786

TRAF1
TNF receptor-associated factor 1

5

2

High-throughput

0.660

High

1244685

NUP35
Nucleoporin NUP35

3

1

High-throughput

0.656

High

1314019

ABI3
ABI gene family member 3

4

1

High-throughput

0.642

High

878147

PKNX1
Homeobox protein PKNOX1

4

3

High-throughput

0.637

High

727310

NU214
Nuclear pore complex protein Nup214

2

15

Small-scale

0.611

High

1299079

WDFY2
WD repeat and FYVE domain-containing protein 2

3

4

High-throughput

0.609

High

1314026

COG6
Conserved oligomeric Golgi complex subunit 6

2

1

High-throughput

0.606

High

1314007

OSBL6
Oxysterol-binding protein-related protein 6

2

0

High-throughput

0.602

High

1314012

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

0

High-throughput

0.602

High

273969

NU155
Nuclear pore complex protein Nup155

2

10

High-throughput

0.584

High

256339

BRE1B
E3 ubiquitin-protein ligase BRE1B

2

1

High-throughput

0.574

High

1067464

EEA1
Early endosome antigen 1

2

3

High-throughput

0.574

High

1283417

RN166
E3 ubiquitin-protein ligase RNF166

2

2

High-throughput

0.558

High

154523

MEIS2
Homeobox protein Meis2

2

3

High-throughput

0.553

High

1189587

K1C28
Keratin, type I cytoskeletal 28

2

1

High-throughput

0.553

High

1189646

K1C27
Keratin, type I cytoskeletal 27

2

1

High-throughput

0.553

High

1296285

PKNX2
Homeobox protein PKNOX2

2

3

High-throughput

0.553

High

1314022

UBQL2
Ubiquilin-2

2

2

High-throughput

0.553

High

834834

RBP2
E3 SUMO-protein ligase RanBP2

1

2

High-throughput

0.536

High

858043

NUP98
Nuclear pore complex protein Nup98-Nup96

1

19

High-throughput

0.536

High

884789

NU107
Nuclear pore complex protein Nup107

1

7

High-throughput

0.536

High

919247

RAN
GTP-binding nuclear protein Ran

1

2

High-throughput

0.536

High

1061227

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

1131254

NU188
Nucleoporin NUP188

1

1

High-throughput

0.536

High

1230809

NUP93
Nuclear pore complex protein Nup93

1

8

High-throughput

0.536

High

1268373

NU205
Nuclear pore complex protein Nup205

1

9

High-throughput

0.536

High

1314025

UBQL1
Ubiquilin-1

1

2

High-throughput

0.523

High

1260657

CHMP7
Charged multivesicular body protein 7

1

1

High-throughput

0.515

High

181244

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

1058874

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.513

High

1312409

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.513

High

647673

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.508

High

626243

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.494

High

1314006

TRI54
Tripartite motif-containing protein 54

1

2

High-throughput

0.494

High

1039379

NDF1
Neurogenic differentiation factor 1

1

0

High-throughput

0.493

High

1260592

BRK1
Protein BRICK1

1

0

High-throughput

0.493

High

1298238

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.493

High

1304866

TSNAX
Translin-associated protein X

1

0

High-throughput

0.493

High

1077110

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.489

High

1283451

SPSB4
SPRY domain-containing SOCS box protein 4

1

3

High-throughput

0.489

High

1307541

GDF15
Growth/differentiation factor 15

1

2

High-throughput

0.489

High

1314015

GDF3
Growth/differentiation factor 3

1

1

High-throughput

0.489

High

163216

XPO1
Exportin-1

1

19

Small-scale

0.479

High

796793

RANG
Ran-specific GTPase-activating protein

1

9

High-throughput

0.479

High

1121107

GLE1
mRNA export factor GLE1

1

5

High-throughput

0.479

High

1168664

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

1200332

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

1

High-throughput

0.479

High

1314020

NXF1
Nuclear RNA export factor 1

1

6

High-throughput

0.479

High

1232246

EH1L1
EH domain-binding protein 1-like protein 1

1

6

High-throughput

0.470

High

277124

STAM2
Signal transducing adapter molecule 2

1

2

High-throughput

0.470

High

785401

ELK3
ETS domain-containing protein Elk-3

1

1

High-throughput

0.470

High

884233

KLF3
Krueppel-like factor 3

1

1

High-throughput

0.470

High

885455

VSX2
Visual system homeobox 2

1

1

High-throughput

0.470

High

1046747

KLF5
Krueppel-like factor 5

1

1

High-throughput

0.470

High

1048478

DPYS
Dihydropyrimidinase

1

1

High-throughput

0.470

High

1049701

DELE1
DAP3-binding cell death enhancer 1

1

1

High-throughput

0.470

High

1119962

RHG29
Rho GTPase-activating protein 29

1

1

High-throughput

0.470

High

1150400

LEG9C
Galectin-9C

1

1

High-throughput

0.470

High

1151631

OTU7B
OTU domain-containing protein 7B

1

2

High-throughput

0.470

High

1157144

ESRP1
Epithelial splicing regulatory protein 1

1

2

High-throughput

0.470

High

1160001

KLC3
Kinesin light chain 3

1

2

High-throughput

0.470

High

1161724

TTC33
Tetratricopeptide repeat protein 33

1

1

High-throughput

0.470

High

1216779

TMTC1
Protein O-mannosyl-transferase TMTC1

1

1

High-throughput

0.470

High

1233328

PNKD
Probable hydrolase PNKD

1

1

High-throughput

0.470

High

1233510

STX19
Syntaxin-19

1

1

High-throughput

0.470

High

1270612

STAM1
Signal transducing adapter molecule 1

1

2

High-throughput

0.470

High

1290043

RNF31
E3 ubiquitin-protein ligase RNF31

1

4

High-throughput

0.470

High

1292475

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

High-throughput

0.470

High

1297975

ZN488
Zinc finger protein 488

1

1

High-throughput

0.470

High

1307559

AKAP9
A-kinase anchor protein 9

1

1

High-throughput

0.470

High

1309817

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

2

High-throughput

0.470

High

1314005

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

1

2

High-throughput

0.470

High

1314009

UBQL3
Ubiquilin-3

1

2

High-throughput

0.470

High

1302264

TM209
Transmembrane protein 209

1

0

High-throughput

0.458

High

233614

NUPR1
Nuclear protein 1

1

1

High-throughput

0.437

High

256039

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

553607

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

652138

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

721331

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

799144

NKX21
Homeobox protein Nkx-2.1

1

2

High-throughput

0.437

High

875279

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.437

High

1085922

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.437

High

1135128

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.437

High

1167240

DPPA3
Developmental pluripotency-associated protein 3

1

2

High-throughput

0.437

High

1171524

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1188805

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1298748

SCLT1
Sodium channel and clathrin linker 1

1

2

High-throughput

0.437

High

1304815

TBX5
T-box transcription factor TBX5

1

1

High-throughput

0.437

High

1308498

B9D2
B9 domain-containing protein 2

1

1

High-throughput

0.437

High

1314021

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

791934

HD
Huntingtin

3

0

High-throughput

0.346

High

1055081

KT33B
Keratin, type I cuticular Ha3-II

3

0

High-throughput

0.344

High

1294971

COG3
Conserved oligomeric Golgi complex subunit 3

3

0

High-throughput

0.344

High

1314018

MS18A
Protein Mis18-alpha

3

0

High-throughput

0.344

High

1284691

MIB2
E3 ubiquitin-protein ligase MIB2

2

0

High-throughput

0.328

High

1291371

CPNE2
Copine-2

2

0

High-throughput

0.328

High

1314017

FBX28
F-box only protein 28

2

0

High-throughput

0.328

High

329931

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

179421

MRP5
ATP-binding cassette sub-family C member 5

1

0

High-throughput

0.279

Low

513890

DMD
Dystrophin

1

0

High-throughput

0.279

Low

1139300

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

1281897

TOP1M
DNA topoisomerase I, mitochondrial

1

0

High-throughput

0.279

Low

1283704

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.279

Low

1285343

PF21A
PHD finger protein 21A

1

0

High-throughput

0.279

Low

1311027

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.279

Low

276121

SPI2
Serpin I2

1

0

High-throughput

0.269

Low

49677

A1A512
KIAA0355 protein

1

0

High-throughput

0.268

Low

49971

F168B
Myelin-associated neurite-outgrowth inhibitor

1

0

High-throughput

0.268

Low

50455

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.268

Low

81587

B7Z3E8
cDNA FLJ51208

1

0

High-throughput

0.268

Low

110699

H3BUJ7
E4F transcription factor 1

1

0

High-throughput

0.268

Low

124934

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.268

Low

174431

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.268

Low

204422

MS18B
Protein Mis18-beta

1

0

High-throughput

0.268

Low

237757

TSN2
Tetraspanin-2

1

0

High-throughput

0.268

Low

267691

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.268

Low

278526

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.268

Low

278658

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.268

Low

308013

ZWINT
ZW10 interactor

1

0

High-throughput

0.268

Low

365287

MT2
Metallothionein-2

1

0

High-throughput

0.268

Low

595683

BCL3
B-cell lymphoma 3 protein

1

0

High-throughput

0.268

Low

622252

CX7A1
Cytochrome c oxidase subunit 7A1, mitochondrial

1

0

High-throughput

0.268

Low

646621

AOFB
Amine oxidase [flavin-containing] B

1

0

High-throughput

0.268

Low

730345

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.268

Low

814014

RGR
RPE-retinal G protein-coupled receptor

1

0

High-throughput

0.268

Low

829058

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.268

Low

883079

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

High-throughput

0.268

Low

945814

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.268

Low

987841

GABP1
GA-binding protein subunit beta-1

1

0

High-throughput

0.268

Low

1012464

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

High-throughput

0.268

Low

1032271

CENPR
Centromere protein R

1

0

High-throughput

0.268

Low

1037093

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.268

Low

1059009

STAT4
Signal transducer and activator of transcription 4

1

0

High-throughput

0.268

Low

1158392

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.268

Low

1168320

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.268

Low

1172624

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.268

Low

1191822

SPT12
Spermatogenesis-associated protein 12

1

0

High-throughput

0.268

Low

1198538

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.268

Low

1199223

YRDC
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.268

Low

1203447

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

High-throughput

0.268

Low

1203534

TEN1L
CST complex subunit TEN1

1

0

High-throughput

0.268

Low

1203631

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

1219334

ARCH
Protein archease

1

0

High-throughput

0.268

Low

1220575

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.268

Low

1221990

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.268

Low

1235937

MET27
Methyltransferase-like protein 27

1

0

High-throughput

0.268

Low

1242487

ICA1L
Islet cell autoantigen 1-like protein

1

0

High-throughput

0.268

Low

1242865

Q8NE08
COL25A1 protein

1

0

High-throughput

0.268

Low

1243785

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.268

Low

1252694

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

0

High-throughput

0.268

Low

1282631

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.268

Low

1282940

TSACC
TSSK6-activating co-chaperone protein

1

0

High-throughput

0.268

Low

1287101

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.268

Low

1288763

ASB9
Ankyrin repeat and SOCS box protein 9

1

0

High-throughput

0.268

Low

1290014

REX1B
Required for excision 1-B domain-containing protein

1

0

High-throughput

0.268

Low

1291423

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.268

Low

1306914

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.268

Low

1308697

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

0

High-throughput

0.268

Low

1309925

Q9BR81
Protocadherin gamma subfamily C, 3

1

0

High-throughput

0.268

Low

1310747

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.268

Low

1311890

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.268

Low

1313406

MTNA
Methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.268

Low

1313629

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.268

Low

1314004

TEX12
Testis-expressed protein 12

1

0

High-throughput

0.268

Low

1314010

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.268

Low

1314013

CD209
CD209 antigen

1

0

High-throughput

0.268

Low

1314014

AMBN
Ameloblastin

1

0

High-throughput

0.268

Low

1314016

GKN1
Gastrokine-1

1

0

High-throughput

0.268

Low

1314023

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.268

Low

1314024

PADI3
Protein-arginine deiminase type-3

1

0

High-throughput

0.268

Low

882536

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1159432

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1314011

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024