HitPredict

Interactor 1: VP37C (A5D8V6)
Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C)
Gene: VPS37C

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	38803224, 23314748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 685
+	Hs
		476399 VP37B_HUMAN (7-246): 1.32e-31: 122: 38.17		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475671 EP300_HUMAN (140-349): 4.17e-26: 112: 21.24		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476066 VP37A_HUMAN (1-157): 3.22e-26: 109: 25.48		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		1091778 SC31B_ARATH (46-299): 1.56e-37: 145: 16.54		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092316 SC24A_ARATH (165-355): 9.91e-10: 62.3: 19.42		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092229 SC24C_ARATH (130-353): 1.08e-09: 62: 15.04		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092118 Q9LIE8_ARATH (94-345): 5.86e-09: 59.7: 13.10		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		924080 VP37A_HUMAN (1-157): 3.22e-26: 109: 25.48		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476909 VP37A_MOUSE (1-155): 1.09e-32: 127: 25.81		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		1144063 SYNJ1_RAT (83-341): 1.74e-25: 110: 18.47		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		397937 EP300_HUMAN (140-349): 4.17e-26: 112: 21.24		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69