Protein: TM218
Transmembrane protein 218

Gene: TM218, TMEM218
Organism: Homo sapiens
Interactions: 78
UniProt ID: A2RU14

Gene Ontology (top 5):
GO:0005929 - cilium
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

60573

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

5

0

High-throughput

0.691

High

60593

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

4

0

High-throughput

0.675

High

60548

TSN12
Tetraspanin-12

2

1

High-throughput

0.606

High

60559

AQP2
Aquaporin-2

2

1

High-throughput

0.606

High

58656

FRMD3
FERM domain-containing protein 3

2

0

High-throughput

0.580

High

60560

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

0

High-throughput

0.580

High

60563

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

60568

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.580

High

60569

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

60576

TM207
Transmembrane protein 207

2

0

High-throughput

0.580

High

60583

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.580

High

60585

GDAP1
Ganglioside-induced differentiation-associated protein 1

2

0

High-throughput

0.580

High

60587

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

60589

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

60591

TM234
Transmembrane protein 234

2

0

High-throughput

0.580

High

60594

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.580

High

60595

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.580

High

60604

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.580

High

60613

CLM8
CMRF35-like molecule 8

2

0

High-throughput

0.580

High

60614

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

60547

CXB6
Gap junction beta-6 protein

2

2

High-throughput

0.553

High

60550

CXB1
Gap junction beta-1 protein

2

2

High-throughput

0.553

High

60555

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.553

High

60557

TRFR
Thyrotropin-releasing hormone receptor

2

1

High-throughput

0.553

High

60565

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

60567

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.553

High

60578

CL17A
C-type lectin domain family 17, member A

2

1

High-throughput

0.553

High

60582

CLC10
C-type lectin domain family 10 member A

2

1

High-throughput

0.553

High

60586

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.553

High

60596

NTCP4
Sodium/bile acid cotransporter 4

2

1

High-throughput

0.553

High

60603

GPR61
G-protein coupled receptor 61

2

1

High-throughput

0.553

High

60605

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.553

High

60611

CXB4
Gap junction beta-4 protein

2

2

High-throughput

0.553

High

60612

ELOV2
Very long chain fatty acid elongase 2

2

1

High-throughput

0.553

High

3400

A0A0S2Z4U3
Syndecan

1

1

High-throughput

0.515

High

60588

Q8WUV1
Tetraspanin

1

3

High-throughput

0.515

High

60545

SDC3
Syndecan-3

1

1

High-throughput

0.481

High

60541

J3KQ12
Seipin

1

1

High-throughput

0.470

High

60572

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

60544

FFAR2
Free fatty acid receptor 2

1

1

High-throughput

0.439

High

60598

BSCL2
Seipin

1

1

High-throughput

0.439

High

60600

TSN18
Tetraspanin-18

1

2

High-throughput

0.439

High

60552

PCNA
Proliferating cell nuclear antigen

2

0

High-throughput

0.337

High

60542

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.316

High

60543

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.316

High

60546

KCNK5
Potassium channel subfamily K member 5

2

0

High-throughput

0.316

High

60551

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

60554

CTLA4
Cytotoxic T-lymphocyte protein 4

2

0

High-throughput

0.316

High

60558

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.316

High

60561

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

60562

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

60564

CLD2
Claudin-2

2

0

High-throughput

0.316

High

60566

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

60570

PKHO1
Pleckstrin homology domain-containing family O member 1

2

0

High-throughput

0.316

High

60571

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

60574

TMM88
Transmembrane protein 88

2

0

High-throughput

0.316

High

60575

TMED8
Protein TMED8

2

0

High-throughput

0.316

High

60577

TM182
Transmembrane protein 182

2

0

High-throughput

0.316

High

60580

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

60581

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

60584

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

60590

ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

2

0

High-throughput

0.316

High

60592

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

60597

P3IP1
Phosphoinositide-3-kinase-interacting protein 1

2

0

High-throughput

0.316

High

60599

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.316

High

60601

PD1L2
Programmed cell death 1 ligand 2

2

0

High-throughput

0.316

High

60602

T106C
Transmembrane protein 106C

2

0

High-throughput

0.316

High

60606

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

60607

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

60609

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.316

High

60610

SAR1A
Small COPII coat GTPase SAR1A

2

0

High-throughput

0.316

High

60615

DGLA
Diacylglycerol lipase-alpha

2

0

High-throughput

0.316

High

60616

NPFF2
Neuropeptide FF receptor 2

2

0

High-throughput

0.316

High

60608

TM231
Transmembrane protein 231

1

0

High-throughput

0.269

Low

60549

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

60553

MUC1
Mucin-1

1

0

High-throughput

0.251

Low

60556

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

60579

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025