HitPredict

Interactor 1: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: IRAK4 (Q8R4K2)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1)
Gene: IRAK4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 30108181, 19378012, 22011580, 16306937, 12538665, 24529375
Identification Methods affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007254 - JNK cascade
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Mm

1 459
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024