HitPredict

Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: USF2 (Q15853)
Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2)
Gene: USF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 17353931, 15014447, 26496610, 28514442, 8576131, 33961781, 16943425, 17846119, 21653943, 19303849
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000430 - regulation of transcription from RNA polymerase II promoter by glucose
GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 11 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 346
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Last updated: 15 Jul 2024