Protein: ALAT1
Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1)

Gene: ALAT1, GPT
Organism: Homo sapiens
Interactions: 15
UniProt ID: P24298

Gene Ontology (top 5):
GO:0004021 - L-alanine:2-oxoglutarate aminotransferase activity
GO:0005829 - cytosol
GO:0009058 - biosynthetic process
GO:0030170 - pyridoxal phosphate binding
GO:0042853 - L-alanine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

664521

ALAT2
Alanine aminotransferase 2

1

17

High-throughput

0.691

High

539774

RALA
Ras-related protein Ral-A

1

0

High-throughput

0.513

High

664514

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

664520

MAEA
E3 ubiquitin-protein transferase MAEA

1

0

High-throughput

0.513

High

664522

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.513

High

132433

CDC7
Cell division cycle 7-related protein kinase

1

3

High-throughput

0.494

High

457043

CAN1
Calpain-1 catalytic subunit

1

1

Small-scale

0.481

High

225536

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

2

High-throughput

0.479

High

664515

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

1

High-throughput

0.479

High

664516

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.479

High

664523

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

1

High-throughput

0.479

High

664513

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.437

High

664518

CUL4A
Cullin-4A

1

6

High-throughput

0.437

High

664517

PLD1
Phospholipase D1

1

0

High-throughput

0.279

Low

664519

SAS6
Spindle assembly abnormal protein 6 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025