Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: X3CL1 (P78423)
Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]
Gene: CX3CL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 802
Hs

1 397
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024