HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 784
+	Hs
		601497 FGFR2_HUMAN (4-797): 0: 737: 56.44		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		507955 FGFR1_HUMAN (3-794): 0: 706: 54.76		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		665468 EPHA8_HUMAN (4-763): 0: 549: 19.79		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		966706 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		384669 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		437757 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		384121 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437718 UFO_HUMAN (5-793): 5.98e-159: 486: 22.59		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		729265 VGFR3_HUMAN (153-356): 9.15e-11: 67.8: 18.78		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		572623 VGFR1_HUMAN (26-128): 1.78e-10: 67: 22.22		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Mm
		519479 PTK7_MOUSE (153-424): 1.52e-19: 96.3: 17.09		PFKAL_MOUSE (19-779): 0: 1023: 69.42
+	Hs
		571668 FGFR3_HUMAN (5-799): 0: 712: 61.07		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571675 EPHA8_HUMAN (4-763): 0: 549: 19.79		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		384225 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571677 UFO_HUMAN (5-793): 5.98e-159: 486: 22.59		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571707 TIE2_HUMAN (25-749): 5.61e-148: 464: 24.97		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571681 VGFR3_HUMAN (153-356): 9.15e-11: 67.8: 18.78		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571663 VGFR1_HUMAN (26-128): 1.78e-10: 67: 22.22		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03