HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 625
+	Hs
		601512 FGFR2_HUMAN (4-797): 0: 737: 56.44		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		508002 FGFR1_HUMAN (3-794): 0: 706: 54.76		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		1057046 EPHA7_HUMAN (4-781): 0: 584: 19.90		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		872443 EPHA5_HUMAN (4-771): 0: 580: 18.81		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		307505 FGFR4_HUMAN (13-802): 0: 750: 100.00		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		508299 FGFR1_HUMAN (3-794): 0: 706: 54.76		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		1057047 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		384843 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		307502 FGFR1_HUMAN (3-794): 0: 706: 54.76		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		434196 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		203204 FGFR1_HUMAN (3-794): 0: 706: 54.76		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29
+	Hs
		307509 EPHA2_HUMAN (4-789): 0: 573: 19.58		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		385817 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		434323 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		384551 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		SC24C_HUMAN (288-606): 1.21e-10: 66.6: 8.96
+	Bt
		94410 F1MWF1_BOVIN (28-376): 4.18e-24: 110: 16.03		F1N579_BOVIN (8-548): 7.3e-68: 233: 22.84
+	Hs
		729709 VGFR2_HUMAN (74-376): 3.42e-24: 111: 16.67		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Mm
		729410 VGFR3_MOUSE (41-369): 3.67e-17: 88.6: 17.74		EPN2_MOUSE (8-555): 6.06e-69: 236: 18.81
+	Mm
		729409 VGFR3_MOUSE (41-369): 3.67e-17: 88.6: 17.74		EPN1_MOUSE (8-529): 2.71e-64: 223: 24.30
+	Hs
		729401 VGFR3_HUMAN (153-356): 9.15e-11: 67.8: 18.78		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55