HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: GRIN1 (Q7Z2K8)
G protein-regulated inducer of neurite outgrowth 1 (GRIN1)
Gene: GPRIN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 1008
+	Hs
		609379 FGFR3_HUMAN (5-799): 0: 712: 61.07		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		508078 FGFR1_HUMAN (3-794): 0: 706: 54.76		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		608021 FGFR4_HUMAN (13-802): 0: 750: 100.00		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Hs
		601536 FGFR2_HUMAN (4-797): 0: 737: 56.44		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Hs
		508073 FGFR1_HUMAN (3-794): 0: 706: 54.76		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Hs
		665620 EPHB2_HUMAN (4-779): 0: 557: 17.27		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		385071 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		674468 UFO_HUMAN (5-793): 5.98e-159: 486: 22.59		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		434228 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		GRIN1_HUMAN (1-1008): 1.34e-71: 259: 100.00
+	Hs
		665617 EPHB2_HUMAN (4-779): 0: 557: 17.27		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Hs
		1083862 NTRK2_HUMAN (114-757): 9.58e-166: 502: 25.84		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Mm
		546296 NTRK2_MOUSE (122-757): 5e-166: 503: 26.62		GRIN1_MOUSE (48-1008): 4.83e-32: 136: 50.82
+	Hs
		434222 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		GRIN3_HUMAN (263-1007): 1.28e-34: 144: 16.48
+	Hs
		385375 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		CIC_HUMAN (71-999): 5.54e-13: 76: 9.53
+	Hs
		311786 RET_HUMAN (221-802): 2.33e-148: 465: 34.72		TACC2_HUMAN (2-1006): 5.38e-09: 62.6: 9.83
+	Dm
		1362400 CAD96_DROME (460-757): 3.19e-81: 278: 45.97		Q9VLS7_DROME (5-746): 6.09e-14: 78.7: 9.19
+	Hs
		729657 VGFR2_HUMAN (74-376): 3.42e-24: 111: 16.67		MDC1_HUMAN (2-1000): 5.32e-30: 131: 7.58
+	Mm
		1113018 PTK7_MOUSE (153-424): 1.52e-19: 96.3: 17.09		GRIN1_MOUSE (48-1008): 4.83e-32: 136: 50.82
+	Hs
		1031137 PTK7_HUMAN (153-424): 7.29e-20: 97.1: 16.36		MTUS2_HUMAN (37-992): 1.18e-10: 68.2: 15.70