HitPredict

Interactor 1: KCNA4 (P22459)
Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4)
Gene: KCNA4

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11997254
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 870
+	Hs
		608232 KCNA4_HUMAN (1-653): 0: 595: 100.00		MPP7_HUMAN (7-359): 1.15e-23: 108: 13.61
+	Hs
		159156 KCNA4_HUMAN (1-653): 0: 595: 100.00		CSKP_HUMAN (24-307): 6.74e-22: 104: 10.62
+	Hs
		608222 KCNA4_HUMAN (1-653): 0: 595: 100.00		EM55_HUMAN (55-375): 1.24e-19: 94.9: 14.07
+	Hs
		608224 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		608221 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Rn
		548174 KCNA4_RAT (1-653): 0: 587: 96.03		DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93
+	Rn
		548175 KCNA4_RAT (1-653): 0: 587: 96.03		DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23
+	Hs
		608244 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40
+	Mm
		1142574 KCNA4_MOUSE (1-653): 0: 576: 96.79		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Rn
		580271 KCNA5_RAT (44-636): 7.42e-156: 464: 55.28		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19
+	Hs
		602905 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		602901 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		608272 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		608268 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Mm
		927733 KCNA2_MOUSE (140-653): 1.88e-150: 446: 65.95		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Hs
		942333 KCNA1_HUMAN (140-653): 2.24e-150: 446: 65.56		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		558713 KCNA2_HUMAN (140-653): 4.02e-150: 445: 65.76		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Mm
		558703 KCNA1_MOUSE (140-653): 8.02e-150: 444: 65.56		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Mm
		558878 KCNA3_MOUSE (151-653): 1.09e-147: 440: 66.40		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Dm
		439922 KCNAS_DROME (119-614): 2.75e-133: 407: 58.38		DLG1_DROME (321-774): 3.5e-09: 62.9: 12.92