HitPredict

Interactor 1: UBA1 (P22515)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45)
Gene: UBA1

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23332755, 19536198, 16429126
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1024 Sc			1 613
+	Sc
		510292 UBA1_YEAST (1-1024): 0: 1089: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		768927 UBA2_YEAST (25-426): 1.8e-67: 240: 16.18		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511998 UBA2_YEAST (25-426): 1.8e-67: 240: 16.18		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		769566 RHC31_YEAST (407-577): 1.41e-41: 158: 22.81		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		512858 RHC31_YEAST (407-577): 1.41e-41: 158: 22.81		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		513398 UBA3_YEAST (434-619): 7.64e-23: 102: 30.46		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		871812 SAE1_HUMAN (409-706): 1.78e-61: 215: 20.46		HSP72_HUMAN (4-612): 0: 888: 60.13
+	Hs
		503435 UBA1_HUMAN (393-622): 1.44e-27: 123: 17.75		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		450199 RHC31_YEAST (407-577): 1.41e-41: 158: 22.81		HSP73_YEAST (9-611): 0: 677: 60.66