HitPredict

Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Interactor 2: ABF2 (Q02486)
ARS-binding factor 2, mitochondrial
Gene: ABF2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1536 Sc			1 183
+	Sc
		609068 SIN3_YEAST (1-1536): 0: 1807: 100.00		IXR1_YEAST (43-114): 3.49e-13: 68.6: 33.33
+	Hs
		1300903 SIN3A_HUMAN (109-525): 1.58e-62: 237: 33.64		CIC_HUMAN (5-151): 4.71e-31: 120: 17.69
+	Hs
		818379 SIN3A_HUMAN (109-525): 1.58e-62: 237: 33.64		SOX2_HUMAN (10-144): 4.99e-32: 118: 17.04
+	Mm
		1141045 SIN3A_MOUSE (126-515): 8.4e-62: 234: 34.47		Q60I23_MOUSE (10-144): 3.4e-31: 116: 17.78
+	Mm
		818710 SIN3A_MOUSE (126-515): 8.4e-62: 234: 34.47		SOX2_MOUSE (10-144): 7.82e-31: 115: 17.78
+	Hs
		257822 SIN3B_HUMAN (185-472): 5.56e-24: 112: 18.81		CIC_HUMAN (5-151): 4.71e-31: 120: 17.69
+	Hs
		257753 SIN3B_HUMAN (185-472): 5.56e-24: 112: 18.81		SOX2_HUMAN (10-144): 4.99e-32: 118: 17.04