HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35384245, 32814053
Identification Methods	proximity labelling technology, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 480
+	Hs
		1081563 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		738254 FLT3_HUMAN (11-791): 1.67e-162: 499: 23.74		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		385330 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		681463 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243425 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		384352 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243251 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243261 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Mm
		1142038 MUSK_MOUSE (40-466): 2.1e-29: 127: 18.06		DNJA3_MOUSE (1-480): 0: 555: 87.50
+	Hs
		729333 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		508145 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		608081 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		681349 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		507875 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243277 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243293 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38