Interactor 1: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Interactor 2: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 11175906, 17261801, 30765471
Identification Methods x-ray crystallography, cross-linking study, comigration in non denaturing gel electrophoresis
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ferrochelatase~Ferrochelatase
Common GO terms GO:0004325 - ferrochelatase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006091 - generation of precursor metabolites and energy
and 26 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 423
Hs

1 423
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024