HitPredict

Interactor 1: ITB5 (P18084)
Integrin beta-5
Gene: ITGB5

Interactor 2: MFGM (Q08431)
Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin]
Gene: MFGE8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 799 Hs			1 387
+	Hs
		229865 ITB5_HUMAN (1-799): 0: 778: 100.00		EDIL3_HUMAN (16-387): 5.18e-165: 472: 47.73
+	Hs
		612117 ITB5_HUMAN (1-799): 0: 778: 100.00		CNTP3_HUMAN (263-387): 2.5e-37: 145: 37.01
+	Dm
		263192 TENM_DROME (517-730): 4.42e-36: 149: 19.67		Q9VU94_DROME (78-387): 3.43e-80: 270: 24.48
+	Mm
		86301 B9EJ72_MOUSE (558-741): 1.62e-26: 119: 17.90		CNTP2_MOUSE (263-387): 8.96e-40: 152: 36.22
+	Hs
		139650 DLL1_HUMAN (483-718): 1.15e-24: 112: 18.01		DDR1_HUMAN (225-387): 2.84e-35: 139: 26.79
+	Mm
		1190260 TEN4_MOUSE (593-738): 9.4e-14: 77.8: 15.03		CNTP2_MOUSE (263-387): 8.96e-40: 152: 36.22
+	Mm
		1423612 TEN1_MOUSE (626-731): 6.61e-10: 65.1: 8.66		CNTP2_MOUSE (263-387): 8.96e-40: 152: 36.22