Interactor 1: PP2B1 (P23287)
Serine/threonine-protein phosphatase 2B catalytic subunit A1 (EC 3.1.3.16) (Calcineurin A1) (Calmodulin-binding protein 1)
Gene: CNA1

Interactor 2: CANB (P25296)
Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit)
Gene: CNB1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 10373463, 11805837, 37968396, 16554755, 17386265, 19285944, 20489023
Identification Methods two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Metallophos
Common GO terms GO:0005955 - calcineurin complex
GO:0006873 - intracellular monoatomic ion homeostasis
GO:0022604 - regulation of cell morphogenesis
GO:0031505 - fungal-type cell wall organization
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 553
Sc

1 175
+ Sp
+ Sc
+ Hs
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024