HitPredict

Interactor 1: S10A1 (P23297)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100A1

Interactor 2: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy, isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0042803 - protein homodimerization activity
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 1960
+	Hs
		685160 S10AB_HUMAN (2-92): 6.83e-36: 119: 41.76		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		638930 S100P_HUMAN (3-92): 3.73e-33: 111: 54.44		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		642921 S10A4_HUMAN (1-90): 5.06e-32: 109: 51.11		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		661212 S10A2_HUMAN (1-90): 1.74e-31: 107: 52.22		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		707357 S10A3_HUMAN (1-90): 4.12e-30: 104: 42.22		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		380748 S100B_HUMAN (3-93): 1.37e-29: 102: 58.24		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		416584 S10A6_HUMAN (1-88): 1.92e-26: 94.5: 44.32		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		707349 S10A5_HUMAN (1-94): 8.03e-25: 90.6: 45.75		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		724898 S1A7A_HUMAN (3-91): 7.74e-20: 78.3: 21.98		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		725028 S10AE_HUMAN (3-84): 7.93e-20: 78.3: 26.83		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		666670 S100G_HUMAN (5-84): 5.27e-19: 75.6: 41.25		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		678418 S10A7_HUMAN (3-91): 9.61e-19: 75.6: 19.78		MYH9_HUMAN (1-1923): 0: 1124: 100.00
+	Hs
		642958 S10A4_HUMAN (1-90): 5.06e-32: 109: 51.11		MYH14_HUMAN (1316-1960): 4.14e-32: 139: 15.50