HitPredict

Interactor 1: SON (P18583)
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)
Gene: SON

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	17353931, 15324660
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2426 Hs			1 247
+	Hs
		615331 SON_HUMAN (1-2426): 0: 653: 100.00		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		71972 CO6A5_HUMAN (64-380): 5.97e-40: 166: 4.07		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		334286 TACC2_HUMAN (26-2267): 6.47e-37: 156: 9.89		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		971924 SCAFB_HUMAN (1309-2042): 9.81e-17: 89.6: 16.07		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		966790 SCAFB_HUMAN (1309-2042): 9.81e-17: 89.6: 16.07		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		971678 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		319058 K0754_HUMAN (81-390): 3.15e-12: 74.9: 16.77		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		966281 PRP4K_HUMAN (1837-2057): 3.73e-14: 80.7: 21.53		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		966501 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		334287 TACC2_HUMAN (26-2267): 6.47e-37: 156: 9.89		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		1049457 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433F_HUMAN (1-246): 2.51e-135: 382: 86.99
+	Mm
		999054 CO6A2_MOUSE (201-340): 4e-09: 64.4: 5.67		1433F_MOUSE (1-246): 1.52e-136: 385: 86.99
+	Hs
		990651 SCAFB_HUMAN (1309-2042): 9.81e-17: 89.6: 16.07		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		729976 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		990385 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		319052 K0754_HUMAN (81-390): 3.15e-12: 74.9: 16.77		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		319061 K0754_HUMAN (81-390): 3.15e-12: 74.9: 16.77		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		691153 OTOG_HUMAN (1375-1776): 7.87e-14: 80.3: 12.86		1433T_HUMAN (2-245): 5.55e-105: 305: 70.33
+	Hs
		990550 TITIN_HUMAN (890-1666): 1.11e-10: 70.1: 9.08		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		691291 TITIN_HUMAN (890-1666): 1.11e-10: 70.1: 9.08		1433T_HUMAN (2-245): 5.55e-105: 305: 70.33