HitPredict

Interactor 1: NELFE (P18615)
Negative elongation factor E (NELF-E) (RNA-binding protein RD)
Gene: NELFE

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	36931259, 37117180
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 246
+	Hs
		615513 NELFE_HUMAN (1-380): 5.15e-92: 282: 100.00		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		615521 NELFE_HUMAN (1-380): 5.15e-92: 282: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		615481 NELFE_HUMAN (1-380): 5.15e-92: 282: 100.00		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		615512 NELFE_HUMAN (1-380): 5.15e-92: 282: 100.00		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		615529 NELFE_HUMAN (1-380): 5.15e-92: 282: 100.00		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Zm
		10840 K7U6V4_MAIZE (245-349): 8.45e-42: 153: 23.64		A0A1D6F6I4_MAIZE (2-241): 2.25e-140: 396: 59.30