Interactor 1: BDNF (P23363)
Brain-derived neurotrophic factor (BDNF) [Cleaved into: BDNF precursor form (ProBDNF)]
Gene: BDNF

Interactor 2: NTRK2 (Q63604)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B)
Gene: NTRK2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27494324
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~NGF
Common GO terms GO:0007612 - learning
GO:0007623 - circadian rhythm
GO:0007631 - feeding behavior
GO:0009416 - response to light stimulus
GO:0010976 - positive regulation of neuron projection development
and 20 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 249
Rn

1 821
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024