HitPredict

Interactor 1: SEC18 (P18759)
Vesicular-fusion protein SEC18
Gene: SEC18

Interactor 2: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	11805837, 18467557, 22615397
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006891 - intra-Golgi vesicle-mediated transport
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Sc			1 889
+	Hs
		773441 NSF_HUMAN (27-755): 1.9e-158: 479: 44.35		COPB2_HUMAN (1-866): 0: 603: 42.48
+	Sc
		679794 CDC48_YEAST (59-538): 1e-73: 257: 22.94		COPB2_YEAST (1-853): 0: 617: 100.00
+	Sc
		679921 CDC48_YEAST (59-538): 1e-73: 257: 22.94		COPA_YEAST (3-887): 1.43e-157: 494: 20.34
+	Hs
		934381 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		WDR5_HUMAN (342-624): 1.02e-49: 180: 11.79
+	Hs
		921847 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		COPA_HUMAN (2-246): 1.15e-35: 148: 15.83
+	Hs
		845261 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		LIS1_HUMAN (307-571): 7.32e-19: 92: 9.03