HitPredict

Interactor 1: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	25273559, 15809305
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0018105 - peptidyl-serine phosphorylation GO:0043066 - negative regulation of apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 1708
+	Hs
		681904 AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		408632 KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		566418 KPCA_HUMAN (4-419): 2.83e-142: 426: 35.55		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1071651 KS6A2_HUMAN (4-412): 5.84e-105: 332: 23.99		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		117012 SGK1_HUMAN (79-417): 5.26e-101: 312: 46.44		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Sc
		520613 YPK1_YEAST (78-421): 5.67e-100: 317: 46.69		TSC11_YEAST (61-991): 0: 911: 24.48
+	Sc
		579940 YPK2_YEAST (78-419): 1.31e-99: 316: 47.54		TSC11_YEAST (61-991): 0: 911: 24.48