HitPredict

Interactor 1: PTPRG (P23470)
Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)
Gene: PTPRG

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	19167335, 21112398
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1445 Hs			1 781
+	Hs
		717099 PTPRK_HUMAN (281-1413): 0: 828: 22.73		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542330 PTPRK_HUMAN (281-1413): 0: 828: 22.73		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		441183 PTPRC_HUMAN (801-1445): 0: 675: 30.00		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		616904 PTPRB_HUMAN (146-1442): 1.22e-116: 407: 14.68		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		617157 PTPRZ_HUMAN (23-885): 2.69e-113: 398: 20.28		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717127 PTPRO_HUMAN (1121-1429): 2.43e-106: 368: 26.03		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		576992 PTPRA_HUMAN (1122-1444): 7.44e-102: 346: 23.94		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		660881 PTPRM_MOUSE (840-1123): 7.39e-60: 229: 26.99		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		489914 PTPRF_HUMAN (201-854): 1.08e-33: 144: 8.97		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		56908 PTPRF_MOUSE (256-833): 1.86e-34: 146: 10.84		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Rn
		1145481 PTPRF_RAT (256-855): 1.08e-33: 144: 10.30		CTNB1_RAT (1-781): 0: 625: 99.74
+	Mm
		472764 PTPRQ_MOUSE (238-868): 1.49e-16: 88: 10.71		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		717036 PTPRJ_HUMAN (296-827): 2.99e-14: 80.3: 9.74		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717247 PTPRU_HUMAN (306-794): 1.68e-10: 68: 8.75		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		489895 PTPRF_HUMAN (201-854): 1.08e-33: 144: 8.97		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Mm
		472765 PTPRQ_MOUSE (238-868): 1.49e-16: 88: 10.71		PLAK_MOUSE (8-752): 6.82e-156: 473: 66.62
+	Dm
		578796 Q9W4F5_DROME (265-888): 1.99e-12: 74.6: 10.23		ARM_DROME (1-780): 9.15e-160: 486: 64.49
+	Dm
		90970 E1JJE4_DROME (265-888): 2.27e-12: 74.2: 10.23		ARM_DROME (1-780): 9.15e-160: 486: 64.49
+	Hs
		542300 PTPRJ_HUMAN (296-827): 2.99e-14: 80.3: 9.74		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Dm
		561758 PTP69_DROME (355-691): 3.59e-11: 70.3: 8.50		ARM_DROME (1-780): 9.15e-160: 486: 64.49