Protein: NLRX1
NLR family member X1 (Caterpiller protein 11.3) (CLR11.3) (Nucleotide-binding oligomerization domain protein 5) (Nucleotide-binding oligomerization domain protein 9)

Gene: NLRX1
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q86UT6

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1116821

AVR2B
Activin receptor type-2B

1

11

High-throughput

0.691

High

1289015

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.691

High

230348

CREB3
Cyclic AMP-responsive element-binding protein 3

3

2

High-throughput

0.667

High

774473

BASI
Basigin

3

3

High-throughput

0.667

High

167923

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

15

Small-scale

0.665

High

1278018

MAVS
Mitochondrial antiviral-signaling protein

3

3

Small-scale

0.650

High

580796

PVR
Poliovirus receptor

2

4

High-throughput

0.628

High

699559

IL1R2
Interleukin-1 receptor type 2

2

3

High-throughput

0.628

High

1204531

HERC4
Probable E3 ubiquitin-protein ligase HERC4

2

6

High-throughput

0.628

High

1289013

LPAR4
Lysophosphatidic acid receptor 4

2

7

High-throughput

0.628

High

177901

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

15

Small-scale

0.618

High

882759

EFTU
Elongation factor Tu, mitochondrial

2

1

Small-scale

0.611

High

1289005

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

2

High-throughput

0.604

High

821738

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.602

High

1289021

NLGN3
Neuroligin-3

2

0

High-throughput

0.602

High

1289027

PCDGD
Protocadherin gamma-B1

2

0

High-throughput

0.602

High

1247695

SARM1
NAD(+) hydrolase SARM1

1

1

High-throughput

0.578

High

1289025

FAF1
FAS-associated factor 1

1

6

Small-scale

0.561

High

132620

UPK1A
Uroplakin-1a

1

2

High-throughput

0.536

High

133274

P2Y10
Putative P2Y purinoceptor 10

1

8

High-throughput

0.536

High

162225

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.536

High

182636

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

537441

HSP7C
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.536

High

716579

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

6

High-throughput

0.536

High

733386

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.536

High

1278399

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.536

High

1289006

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1289020

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1289024

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.536

High

1289028

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.536

High

1094922

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.515

High

1289026

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.515

High

1289030

NEMO
NF-kappa-B essential modulator

1

6

Small-scale

0.515

High

221459

OX2R
Orexin receptor type 2

1

0

High-throughput

0.513

High

270215

ADA11
Disintegrin and metalloproteinase domain-containing protein 11

1

0

High-throughput

0.513

High

376619

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

378635

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

388238

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

407192

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

749354

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.513

High

873862

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

1238400

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

1272927

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.513

High

1289002

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1289003

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.513

High

1289007

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1289010

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

1289014

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1289023

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

372454

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.489

High

214446

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

7

High-throughput

0.479

High

851072

LPAR6
Lysophosphatidic acid receptor 6

1

7

High-throughput

0.479

High

1113568

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1126714

BECN1
Beclin-1

1

6

Small-scale

0.479

High

1289004

STING
Stimulator of interferon genes protein

1

2

Small-scale

0.479

High

1289012

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

418697

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

0

High-throughput

0.458

High

651828

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

Small-scale

0.458

High

1178226

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1252881

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

1289008

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

0

Small-scale

0.458

High

166337

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

844816

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.445

High

877687

SL9A3
Sodium/hydrogen exchanger 3

1

2

High-throughput

0.445

High

1010937

BAT1
b(0,+)-type amino acid transporter 1

1

2

High-throughput

0.445

High

1060366

SLC31
Amino acid transporter heavy chain SLC3A1

1

1

High-throughput

0.445

High

1194522

SL9C1
Solute carrier family 9 member C1

1

1

High-throughput

0.445

High

1240887

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.445

High

1243620

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.445

High

1289009

DNJB8
DnaJ homolog subfamily B member 8

1

6

High-throughput

0.445

High

1289017

S2532
Solute carrier family 25 member 32

1

3

High-throughput

0.445

High

1289019

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.445

High

1289029

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

342607

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.426

High

1219504

ANR22
Ankyrin repeat domain-containing protein 22

1

5

High-throughput

0.407

High

71224

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

1022416

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1213639

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1289016

BRNP2
BMP/retinoic acid-inducible neural-specific protein 2

1

0

High-throughput

0.279

Low

1289018

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.279

Low

377634

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

589058

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695847

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

1010062

DLK1
Protein delta homolog 1

1

0

High-throughput

0.249

Low

1289022

UVRAG
UV radiation resistance-associated gene protein

1

0

Small-scale

0.249

Low

1289011

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025