Interactor 1: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1

Interactor 2: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_ligase_A_C~DNA_ligase_A_M, DNA_ligase_A_C~DNA_ligase_A_N, DNA_ligase_A_M~DNA_ligase_A_M, DNA_ligase_A_M~DNA_ligase_A_N, DNA_ligase_A_N~DNA_ligase_A_N
Common GO terms GO:0003677 - DNA binding
GO:0003909 - DNA ligase activity
GO:0003910 - DNA ligase (ATP) activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 13 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 919
Hs

1 919
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs

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Last updated: 11Aug2025