Interactor 1: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1
Interactor 2: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31839598 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_ligase_A_C~DNA_ligase_A_M, DNA_ligase_A_C~DNA_ligase_A_N, DNA_ligase_A_M~DNA_ligase_A_M, DNA_ligase_A_M~DNA_ligase_A_N, DNA_ligase_A_N~DNA_ligase_A_N |
| Common GO terms | GO:0003677 - DNA binding GO:0003909 - DNA ligase activity GO:0003910 - DNA ligase (ATP) activity GO:0005524 - ATP binding GO:0005634 - nucleus and 13 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025