Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: IRF4 (Q64287)
Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP)
Gene: IRF4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10590072
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF, IRF-3~IRF-3
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002376 - immune system process
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 424
Mm

1 450
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024