HitPredict

Interactor 1: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1241 Hs			1 196
+	Hs
		588583 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		588576 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		588581 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545205 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436156 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		588588 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		588571 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		588572 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564410 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120302 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		530865 AT1A3_HUMAN (27-1052): 0: 766: 24.34		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		393152 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		393135 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		393147 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		393014 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		392986 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		393129 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		393131 AT1A1_HUMAN (34-1053): 0: 737: 23.37		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		393020 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120275 AT1A1_HUMAN (34-1053): 0: 737: 23.37		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98