HitPredict

Interactor 1: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Interactor 2: GP173 (Q9NS66)
Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3)
Gene: GPR173

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1241 Hs			1 373
+	Hs
		428921 AT2B4_HUMAN (1-1241): 0: 1300: 100.00		ADRB2_HUMAN (3-363): 3.95e-69: 224: 16.03
+	Hs
		208448 AT2B4_HUMAN (1-1241): 0: 1300: 100.00		OX2R_HUMAN (17-368): 1.99e-65: 216: 14.67
+	Hs
		208456 AT2B3_HUMAN (1-1241): 0: 1164: 71.63		OX2R_HUMAN (17-368): 1.99e-65: 216: 14.67
+	Hs
		966891 AT2B2_HUMAN (3-1241): 0: 1154: 68.59		GP173_HUMAN (1-373): 2.39e-69: 224: 100.00
+	Hs
		588679 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		GP173_HUMAN (1-373): 2.39e-69: 224: 100.00
+	Hs
		208453 AT2B2_HUMAN (3-1241): 0: 1154: 68.59		OX2R_HUMAN (17-368): 1.99e-65: 216: 14.67
+	Hs
		658239 AT2B3_HUMAN (1-1241): 0: 1164: 71.63		5HT2C_HUMAN (42-366): 1.15e-61: 206: 16.36
+	Hs
		658222 AT2B2_HUMAN (3-1241): 0: 1154: 68.59		5HT2C_HUMAN (42-366): 1.15e-61: 206: 16.36
+	Hs
		530983 AT1A3_HUMAN (27-1052): 0: 766: 24.34		GP173_HUMAN (1-373): 2.39e-69: 224: 100.00
+	Hs
		392982 AT1A1_HUMAN (34-1053): 0: 737: 23.37		ADRB2_HUMAN (3-363): 3.95e-69: 224: 16.03
+	Hs
		1274539 AT2A3_HUMAN (46-1060): 0: 733: 24.89		GP173_HUMAN (1-373): 2.39e-69: 224: 100.00
+	Hs
		428908 AT2A2_HUMAN (45-1066): 0: 733: 25.98		ADRB2_HUMAN (3-363): 3.95e-69: 224: 16.03