HitPredict

Interactor 1: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Interactor 2: RPN5 (Q12250)
26S proteasome regulatory subunit RPN5 (Proteasome non-ATPase subunit 5)
Gene: RPN5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32868373, 37968396, 21289098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 250 Sc			1 445
+	Hs
		121942 PSA5_HUMAN (3-250): 9.42e-92: 272: 30.04		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121938 PSA4_HUMAN (1-247): 4.63e-91: 270: 34.40		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121979 PSA6_HUMAN (2-250): 4.86e-91: 270: 32.54		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121892 PSA7_HUMAN (1-248): 8.69e-90: 267: 32.00		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121936 PSA2_HUMAN (1-250): 3.12e-90: 267: 56.97		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Dm
		771297 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		PSD11_DROME (21-435): 1.22e-90: 282: 12.41
+	Dm
		771304 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		CSN4_DROME (68-437): 2.53e-86: 271: 19.27
+	Hs
		893638 PSA6_HUMAN (2-250): 4.86e-91: 270: 32.54		CSN2_HUMAN (17-426): 1.57e-95: 296: 13.27
+	Hs
		121689 PSA5_HUMAN (3-250): 9.42e-92: 272: 30.04		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Hs
		121685 PSA4_HUMAN (1-247): 4.63e-91: 270: 34.40		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Hs
		121719 PSA6_HUMAN (2-250): 4.86e-91: 270: 32.54		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Dm
		1180708 PSA5_DROME (3-250): 5e-93: 275: 30.59		PSD11_DROME (21-435): 1.22e-90: 282: 12.41
+	Hs
		121635 PSA7_HUMAN (1-248): 8.69e-90: 267: 32.00		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Hs
		121684 PSA2_HUMAN (1-250): 3.12e-90: 267: 56.97		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Sp
		293717 PSA2_SCHPO (1-250): 7.84e-92: 272: 66.00		RPN6_SCHPO (25-432): 2.33e-86: 272: 12.95
+	Sc
		619525 PSA2_YEAST (1-250): 4.68e-95: 280: 100.00		RPN6_YEAST (8-434): 2.76e-73: 238: 10.58
+	Sc
		619398 PSA3_YEAST (4-214): 4.62e-42: 145: 37.09		RPN5_YEAST (1-445): 1.91e-114: 344: 100.00
+	Sp
		1013779 PSA4_SCHPO (5-214): 2.08e-41: 144: 38.39		RPN6_SCHPO (25-432): 2.33e-86: 272: 12.95
+	Sc
		619400 PSA3_YEAST (4-214): 4.62e-42: 145: 37.09		RPN6_YEAST (8-434): 2.76e-73: 238: 10.58