HitPredict

Interactor 1: PAX7 (P23759)
Paired box protein Pax-7 (HuP1)
Gene: PAX7

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 1281
+	Hs
		641591 PAX6_HUMAN (31-449): 6.24e-65: 218: 34.76		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		973890 PAX2_HUMAN (27-380): 2.94e-46: 168: 30.96		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		988816 PAX8_HUMAN (30-462): 9.18e-41: 154: 28.51		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		878476 PAX9_HUMAN (36-186): 4.66e-40: 149: 64.24		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1354245 LHX3_HUMAN (218-462): 2.71e-34: 135: 19.59		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1281197 LHX4_HUMAN (183-462): 5.39e-30: 122: 17.14		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		620222 PAX7_HUMAN (1-505): 4.73e-137: 407: 100.00		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		641600 PAX6_HUMAN (31-449): 6.24e-65: 218: 34.76		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		1033698 LHX4_HUMAN (183-462): 5.39e-30: 122: 17.14		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Ce
		105782 PAX3H_CAEEL (28-318): 1.08e-61: 206: 40.89		ZTF16_CAEEL (895-1271): 2.86e-57: 208: 18.77
+	Hs
		1332093 LHX3_HUMAN (218-462): 2.71e-34: 135: 19.59		IKZF5_HUMAN (909-1270): 9.35e-58: 207: 17.46
+	Hs
		798819 PAX9_HUMAN (36-186): 4.66e-40: 149: 64.24		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Dm
		1229479 Q8MZ02_DROME (151-459): 1.69e-38: 146: 20.19		Q9VF00_DROME (824-1088): 1.87e-41: 166: 20.82
+	Hs
		554427 PITX1_HUMAN (158-406): 7.28e-46: 164: 28.18		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Ce
		105777 PAX3H_CAEEL (28-318): 1.08e-61: 206: 40.89		ELT6_CAEEL (887-997): 4.1e-23: 104: 32.74
+	Ce
		105816 PAX3H_CAEEL (28-318): 1.08e-61: 206: 40.89		EHN3_CAEEL (1128-1269): 5.94e-24: 104: 21.92
+	Hs
		799003 ALX4_HUMAN (138-398): 1.16e-34: 136: 25.82		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Dm
		112555 M9NCY1_DROME (208-408): 5.74e-45: 164: 27.80		Q9VKZ0_DROME (894-1037): 6.07e-24: 111: 20.95
+	Dm
		114764 M9PD53_DROME (208-408): 6.07e-44: 164: 27.80		Q9VKZ0_DROME (894-1037): 6.07e-24: 111: 20.95
+	Hs
		620377 ZFHX4_HUMAN (4-465): 3.51e-17: 87.4: 15.29		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60